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Collaborative Integration, Publishing and Analysis of Distributed Scholarly Metadata
(2019-02-25)
Research is becoming increasingly digital, interdisciplinary, and data-driven and affects different environments in addition to academia, such as industry, and government. Research output representation, publication, mining, ...
Patientenspezifische induziert pluripotente Stammzellen als Modellsystem zur Untersuchung der lysosomalen Speichererkrankung Metachromatische Leukodystrophie
(2019-02-14)
Die Metachromatische Leukodystrophie (MLD) wird verursacht durch eine funktionelle Defizienz des metabolischen Enzyms Arylsulfatase A (ARSA). Unter physiologischen Bedingungen baut ARSA das Membranlipid 3'-O-Sulfo-Galakt ......
Multi-scale modeling of water resources in a tropical inland valley and a tropical floodplain catchment in East Africa
(2019-02-12)
This study investigated the dynamics of hydrological processes at the wetland-catchment scale through field scale-based analysis, point scale modeling using Hydrus-1D model along a floodplain transect in Tanzania and ...
Integrated terrestrial simulations at the continental scale: Impact of groundwater dynamics and human water use on groundwater-to-atmosphere feedbacks during the European heatwave in 2003
(2019-02-19)
The availability of freshwater under current and future climatic conditions remains one of the main research topics that requires an improved understanding of the terrestrial system and anthropogenic impacts. Yet, hydrologic ...
Impact Assessment of Land-Use Change and Agricultural Treatments on Greenhouse Gas Emissions from Wetlands of Uganda and Tanzania
(2020-02-04)
Wetlands play an important role in global climate regulation as they represent a great global carbon sink. Moreover, wetlands provide optimal conditions for food production and support the livelihoods of many people in ...
Functional in vivo calcium imaging in the hippocampus under healthy and disease conditions
(2020-04-22)
The hippocampus has long been known to be essential for all features of memory processing. Hippocampal function strongly depends on the orchestrated activity of transiently autonomous neuronal populations that create the ......
Geometry of random 3-manifolds
(2020-01-31)
We study random 3-manifolds, as introduced by Dunfield and Thurston, from a geometric point of view. Within this framework, work of Maher allows us to equip a typical random 3-manifold with a canonical geometric structure, ...
Characterization and application of fusogenic liposomes
(2020-02-03)
Conventional drug delivery strategies use the endocytic pathway to introduce biomolecules like proteins, DNA, or antibiotics into living cells. The main disadvantage of endocytic uptake is the quick intercellular degradation ......
The role of diacylglycerol acyltransferase 1 in hepatic medium-chain fatty acid metabolism
(2020-01-28)
Fatty acids form a class of important biomolecules, serving as essential elements of lipid molecules. Stored in triacylglycerol (TAG), the main constituent of plant oils and animal fats, they from an inseparable part of ......
Low Dimensional Gauge Theories and Quantum Geometry
(2020-10-14)
This thesis explores the connection between supersymmetric gauge theories on curved spaces of dimensions two and three and geometries that arise in string theory. It does so by studying quantum field theoretic objects such ......