E-Dissertationen: Suche
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Stabilitäts- und Metabolismusuntersuchungen neuer purinerger Wirkstoffe und Ectonucleotidase-Inhibitoren mittels HPLC-DAD-MS(/MS)
(2014-02-14)
Ziel der vorliegenden Arbeit war die Etablierung und Durchführung von Stabilitäts- und Metabolismusuntersuchungen verschiedener im Arbeitskreis synthetisierter neuer Wirkstoffe. Hochpotente und –selektive Nukleotidase-Inhibitoren, ...
Three-dimensional Laser-based Classification in Outdoor Environments
(2014-02-18)
Robotics research strives for deploying autonomous systems in populated environments, such as inner city traffic. Autonomous cars need a reliable collision avoidance, but also an object recognition to distinguish different ...
Die wasserspeichernden Federn der Flughühner (Pteroclididae): Funktionsmorphologie, Benetzungseigenschaften & technischer Nachbau
(2014-02-14)
Flughühner (Pteroclididae) leben in den Trockengebieten Afrikas und Asiens. Die Altvögel tragen über große Strecken Wasser zu ihren Jungen, das sie in ihren Brustfedern transportieren. Obwohl bisher schon einige Publikationen ...
Interlacing Patterns in Exclusion Processes and Random Matrices
(2014-02-11)
In the last decade, there has been increasing interest in the fields of random matrices, interacting particle systems, stochastic growth models, and the connections between these areas. For instance, several objects that ...
The knowledge-based search for water-related information system for the Mekong delta, Vietnam
(2014-03-14)
In recent years, the World Wide Web has strongly changed way of sharing and accessing data. Moreover, with new methods of data collection are developed we have much more data today. However, it is not straightforward to ...
Visibility Domains and Complexity
(2014-02-05)
Two problems in discrete and computational geometry are considered that are related to questions about the combinatorial complexity of arrangements of visibility domains and about the hardness of path planning under cost ...
Functional analyses of the conserved Cysteine-rich with EGF-like domains (Creld) protein family in Mus musculus
(2014-03-28)
The Cysteine-rich with EGF-like domains (Creld) protein family is highly conserved between species. However, its physiological function remained elusive. Using Creld1 knock-out (Creld1KO) mice, Creld1 was identified as an ......
Magnetisation of the IGM: Role of Starburst Dwarf Galaxies
(2014-01-30)
Magnetic fields are ubiquitous in the Cosmos. They are observed on all scales -- from our solar system to galaxy clusters millions of light years away. The dynamo theory and the theory of gravitational compression during ...
Synthese und Charakterisierung neuer fluoreszenzmarkierter Adenosinrezeptor-Liganden als pharmakologische Sonden
(2014-03-26)
G-Protein-gekoppelte Rezeptoren stellen für einen Großteil der zugelassenen Arzneistoffe die Zielstruktur dar und haben somit eine herausragende therapeutische Relevanz. Um detailliertere Informationen über die Interaktion ......
Integrative Systems Approaches Towards Brain Pharmacology and Polypharmacology
(2014-05-02)
Polypharmacology is considered as the future of drug discovery and emerges as the next paradigm of drug discovery. The traditional drug design is primarily based on a “one target-one drug” paradigm. In polypharmacology, ......