E-Dissertationen: Suche
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Eine Interaktionsanalyse des Nod-like-Rezeptors NLRP7: Interdomän-spezifische Analysen und die Identifizierung neuer Proteininteraktionen
(2015-01-14)
Mutationen in NLRP7 (NOD-Like Receptor family, pyrin domain containing 7) sind für das wiederholte Auftreten von biparentalen Blasenmolen (BiBMs) verantwortlich. Typische Merkmale dieser abnormalen Schwangerschaft sind ein ...
The Cytoskeleton of Diatoms: Structural and Genomic Analysis
(2015-01-08)
The cytoskeleton is essential for many cellular functions such as cell motility, the control of cell shape and polarity, meiosis, cytokinesis, intracellular transport as well as endo- and exocytosis. The present study ...
Tracing the Evolution of Local Universe Galaxies by Kinematical Studies of HI
(2015-01-14)
This work studies the neutral gas in external galaxies using the neutral atomic hydrogen (HI) line to investigate the kinematics of the gas component. This thesis consists of three parts, one part focusses on early-type ...
Synthesis of ganglioside and lysoganglioside lipoforms as internal standards for MS quantification
(2015-01-08)
The goal of this work was to establish methods for the synthesis of modified gangliosides that are suitable as internal standards for mass spectrometry. Quantification of gangliosides is usually achieved by staining after ...
Dynamic triggering: The effects of remote earthquakes on volcanoes, hydrothermal systems and tectonics
(2015-02-02)
Dynamic stresses induced by seismic waves from large earthquakes can trigger a variety of geologic phenomena. This thesis focuses on observational evidence of dynamically triggered seismic activity in hydrothermal, volcanic ...
New bioactive metabolites from the marine-derived fungus Dichotomomyces cejpii and their pharmacological relevance
(2015-01-13)
Natural products from fungal sources provide an astonishing diversity of bioactive molecules. The secondary metabolite production in fungi is strongly affected by environmental influences and the isolation of fungal strains ......
Investigation of two different aspects of stem cell biology: The role of Stat3 signaling and innate immunity in human pluripotent stem cells
(2015-01-08)
Human pluripotent stem cells (hPSCs) hold great promises as a model for development as well as a source for cells in regenerative medicine. Although hPSC research came into focus in the last decade, many aspects of the ...
Neuropeptides in stress reactivity: Role of enkephalin in response to chronic stress
(2015-01-29)
The incidence of mood pathologies, such as chronic anxiety and major depression, is a serious health problem in modern societies. The knowledge about the molecular mechanisms involved in the development of these disorders ...
The effect of climate variability on wheat in Iran
(2015-01-22)
In this study, we investigated the impact of temperature variability on wheat phenology in Iran. Temperature is the most appropriate climate variable affecting wheat production wheat in cultivation under irrigation in Iran. ...
Microglial sialic-acid-binding immunoglobulin-like lectin-H (Siglec-H) and Siglec-11 in neuroinflammation
(2015-01-16)
Sialic acid binding Siglecs are involved in various pathological processes. A minor fraction of Siglecs mediates activating signals via the ITAM linked DAP12 adaptor protein while the majority of Siglecs modulates inflammatory ......