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Identification of cisplatin resistance mechanisms and alternative treatment options for testicular germ cell tumors
(2023-06-21)
Type II testicular germ cell tumors (TGCTs) are the most prevalent tumors in young men aged 18 to 35 years. TGCTs are classified as seminomas and non-seminomas. Embryonal carcinomas (EC), representing the cancer stem cell ...
Biosynthesis and Analysis of 3-Isobutyl-2-methoxypyrazine in Capsicum annuum (Bell Pepper) Plants
(2023-06-21)
3-Alkyl-2-methoxypyrazines (MPs) are highly odorous compounds occurring in a wide range of raw vegetables. Due to their high odor activity, they have been of great research interest. The most prominent MPs are 3-isopropy ...
Automatic Evaluation of Dialogue-Systems Using Neural-Network Methods
(2023-06-05)
We usually interact with computers by means of specialized tools that are not as common as the language humans use. This has motivated researchers for already several decades to develop algorithms that enable interfacing ...
Towards a measurement of the tHq process in channels with hadronic tau lepton decays
(2023-10-05)
This thesis presents the first study to find events of the rare tHq process with ATLAS data in channels with hadronically decaying τ. A baseline framework is developed to select as many signal events as possible in ...
AI Models for Modeling and Simulation of Clinical Studies for Alzheimer's and Parkinson's Disease
(2023-08-14)
Neurodegenerative diseases (NDDs) have a complex structure and most of them are untreatable that’s why more research studies undertake translational paths for getting better insights into prevention, early detection, and ...
Climate variability and change in the Altai-Dzungarian region and its hydrological impact
(2023-10-09)
The Altai Mountains and also other mountainous areas of Central Asia experienced intermittent cold periods during the 20th-century warming of the Northern Hemisphere. Since the recent cold period in the 1980s, subsequent ...
Studying Conformational Changes of Biomolecules with Spatiotemporal Resolution and in cell using Pulsed Dipolar EPR Spectroscopy
(2023-08-29)
The function of biomolecules is closely linked with their structure and dynamics. Furthermore, the interconversion of different conformations of a biomolecule determines its activity and is vital for biomolecular processes. ......
Integrated structural biology investigation of the bacterial TRAP transporter SiaPQM from pathogenic bacteria
(2023-10-31)
Sialic acid is utilized by human pathogens like Vibrio cholerae in various ways to colonize the host. Upon contamination it scavenges the sialic acid from mucus-rich parts of the body such as the gut and causes the disease ......
Gravity Tests with Pulsars Using New-Generation Radio Telescopes
(2023-05-23)
Pulsar timing is a powerful tool for studying a wide range of questions in fundamental physics, including the equation of state (EOS) of super-dense matter, tests of general relativity (GR) and alternative theories of ...
Dynamics of group II introns in plant mitogenomes and rickettsial DNA invasions in the mitogenome of Haplopteris ensiformis
(2023-07-27)
The complexity of mitochondrial genomes (mtDNA) in vascular plants is well-known, with factors such as repetitive sequences, variable structural organization, gene synteny decline, high intron content, and RNA editing ...