E-Dissertationen: Search
Now showing items 3891-3900 of 4104
Internally Contracted Multireference Coupled-Cluster Theories With Automated Code Generation
(2023-05-22)
Developing a coupled-cluster theory based on a multiconfigurational reference wave function still is one of the most challenging problems in quantum chemistry, both from a theoretical and implementational perspective. ...
Investigating pathomechanisms underlying malformations of human cortical development
(2023-06-15)
During human development the brain has to form a complex neuronal network requiring a well-orchestrated sequence of neurogenesis, neuronal migration and correct positioning within cortical layers followed by synaptogenesis. ...
Computational Modeling of Complex Chemical Transformations in Homogeneous Catalysis
(2023-09-18)
Catalysis is involved in most manufactured products and hence it is highly important for supplying the society with energy, food, pharmaceuticals and other goods. In recent years, increasing attention has been paid to the ......
Advancing Knowledge-Enhanced Conversational Systems Leveraging Language Models
(2023-09-18)
Large language models empowering recent conversational systems such as Alexa and Siri require external knowledge to generate informative and accurate dialogues. The knowledge may be provided in structured or unstructured ...
Dynamic Local Usage in BonnRouteGlobal
(2023-12-14)
In this dissertation we consider the global routing problem which is a central task in chip design. Up to millions of sets of pins on a chip, so called nets, have to be connected through wires without intersecting each ...
A dark quencher genetically encodable voltage indicator (dqGEVI) for high fidelity recordings in murine and human in vitro systems
(2023-12-04)
To understand neurons and neural circuits it is necessary to visualize their electrical activity.
In contrast to traditional electrophysiological techniques, optical methods are very promising as they tend to ...
In contrast to traditional electrophysiological techniques, optical methods are very promising as they tend to ...
Complement receptors 3 and 4 in kidney diseases
(2023-12-11)
CR3 and CR4 are among the most abundant molecules on the cell surface of DCs, monocytes/macrophages, and PMNs. Both integrins recognize common ligands among which are iC3b, ICAM-1, and fibrinogen. iC3b is generated as a ......
Ultra-high field NMR spectroscopy of GABA in the human brain
(2023-08-31)
Magnetic resonance imaging (MRI) is a non-invasive and radiation-free imaging method that has been utilized in medicine for decades. Using magnetic fields, the nuclear spins within the tissue are perturbed, and the resulting ......
Investigating the effects of sphingosine-1-phosphate lyase (SGPL1) ablation in mouse embryonic fibroblasts and primary astrocytes
(2023-09-13)
Sphingosine-1-phosphate (S1P) is a bioactive lipid that plays a crucial role in various fundamental processes, including cellular proliferation, survival, migration, as well as inflammation. Additionally, it has been ......
The dense interstellar medium and star formation across the nearby galaxies NGC 3627 and NGC 253
(2023-10-11)
The star formation process is an essential aspect of galaxy evolution. Observations of star-forming regions from sub-pc to kpc scales revealed a tight correlation between star formation and the emission of high-critical ...