E-Dissertationen: Suche
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Komplexe dynamische Systeme als funktionelle Netzwerke: Möglichkeiten und Grenzen der datengetriebenen Analyse
(2012-03-12)
Aus einer Vielzahl von Subsystemen zusammengesetzte dynamische Systeme können als Netzwerk aufgefasst und mit Methoden der Graphentheorie beschrieben werden. Innerhalb dieses Ansatzes werden die Subsysteme durch Knoten und ...
RIMs and RIM interacting proteins: localization and function under physiological and pathophysiological conditions
(2011-02-25)
Neurons transmit signals to their target cells at specialized contact sites called synapses. At chemical synapses the signal propagation is mediated by the fusion of neurotransmitter filled synaptic vesicles with the ...
Levetiracetam and Brivaracetam: Synthesis of Radioligands as Pharmacological Tools for Studying Their Interactions with Target Proteins
(2012-12-04)
Epilepsy is one of the most common neurological disorders affecting more than 50 million people worldwide. Despite extensive efforts in antiepileptic drug (AED) development it is estimated that around 30% of all epileptic ...
Copy number variations of the mitochondrial DNA as potential cause of mitochondrial diseases
(2010-12-30)
Aim: The aim of this thesis was the analysis of copy number variations of the mitochondrial DNA (mtDNA) in several tissues and cell types with regard to different mitochondrial associated disorders.
Background: The ...
Background: The ...
The contribution of the sodium channel subunit NaV1.6 to neuronal excitability
(2010-04-13)
The focus of this work was to elucidate the contribution of a single Na+ channel a-subunit, namely NaV1.6, to the discharge properties of CA1 pyramidal neurons. In the first part of this work, we show ...
Reconstructing Human Motion
(2018-05-22)
This thesis presents methods for reconstructing human motion in a variety of applications and begins with an introduction to the general motion capture hardware and processing pipeline.
Then, a data-driven method for ...
Then, a data-driven method for ...
Knotenwichtigkeiten in räumlich ausgedehnten dynamischen Systemen
(2018-08-28)
Ausgedehnte komplexe dynamische Systeme können eine Vielzahl von faszinierenden emergenten Phänomenen aufweisen. Viele solcher Systeme bestehen aus einer großen Anzahl interagierender Subsysteme. Es bietet sich daher an, ...