E-Dissertationen: Search
Now showing items 1-3 of 3
Investigation of BCRP-inhibitors using QSAR and machine learning methods
(2019-08-05)
BCRP is the second member of the subfamily G of the ABC transporters. BCRP is involved in several physiological functions, including protection of the human body from xenobiotics. The overexpression of this membrane protein ...
Dissecting patient heterogeneity via statistical modeling based on multi-modal omics data
(2019-06-27)
One of the key goals of modern medicine is to treat patients individually, recognizing the heterogeneity that exists within them and thus hoping to provide them with more effective personalized therapies. '-Omics' patient ...
Analysis of Multitarget Activities and Assay Interference Characteristics of Pharmaceutically Relevant Compounds
(2019-05-29)
The availability of large amounts of data in public repositories provide a useful source of knowledge in the field of drug discovery. Given the increasing sizes of compound databases and volumes of activity data, computational ...