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Neurotransmitter receptors in mouse models of Alzheimer’s disease
(2014-06-20)
Alzheimer's disease (AD) is the most common form of dementia. The disease occurs in a common sporadic and a familiar form (FAD). Both forms show a very similar clinical and pathological picture, with ß-amyloid (Aß) plaques ...
A Knowledge-based Integrative Modeling Approach for In-Silico Identification of Mechanistic Targets in Neurodegeneration with Focus on Alzheimer’s Disease
(2014-05-21)
Dementia is the progressive decline in cognitive function due to damage or disease in the body beyond what might be expected from normal aging. Based on neuropathological and clinical criteria, dementia includes a spectrum ...