E-Dissertationen: Search
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Implementation of the novel high-throughput Fungal Isolation one step Device method FIND and secondary metabolite extraction from the isolate Heydenia cf. alpina
(2021-07-13)
Fungi are an important source of bioactive metabolites. The cultivation of source organisms is a crucial step in natural product isolation. With standard isolation methods for fungi it is difficult to isolate rare und ...
Total Synthesis of Farnesyl Lipid I/II Analogs and Contributions to the Total Synthesis of Vancoresmycin
(2021-04-21)
Rapidly occurring bacterial resistance against approved medication is steadily increasing and represents an enormous threat for the human health in all parts of the world. Based on the burden of antibiotic resistance and ...
Investigations into side chain assembly and attachment during biosynthesis of the G protein inhibitor FR900359
(2021-06-07)
The natural product FR900359 (FR) selectively inhibits Gaq proteins and thus intracellular signalling of many G protein-coupled receptors. This unique mechanism of action makes FR an indispensable pharmacological tool to ......