E-Dissertationen: Suche
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Advanced population pharmacokinetic modelling to quantify selected characteristics of drugs
(2010-08-03)
The ophthalmic lyophilisate formulation has been known for its safety, tolerability, and ability to achieve higher concentrations of a drug in the internal tissue of the eye compared with the conventional eye drop. Based ...
Migration of interneuronal precursor cells in the developing cerebellum of mice: model-based cell tracking and simulation
(2010-12-10)
The navigation of precursor cells of inhibitory interneurons from their germinal zone inside the fourth ventricle through the white matter towards their final destination within the cerebellum's molecular layer is an ongoing ...
Regulatorische Funktion der Phosphorylierung von Neprilysin in der Lokalisation an der Plasmamembran und der Interaktion mit dem Tumorsuppressor PTEN
(2010-04-23)
Bei der Zink-Metalloendopeptidase Neprilysin (NEP) handelt es sich um ein Typ 2 Membranprotein, das für die Degradation von extrazellulären Peptiden und Peptidhormonen zuständig ist. Darüber hinaus kann NEP sowohl im ......