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Distinct dynamics and kinetics determine efficient antigen-presentation by LSEC and support IL-2 dependent CD8 T cell activation
(2009-05-25)
Liver sinusoidal endothelial cells (LSEC) have important clearance and immune regulatory functions, acting as unique organ resident APC. Soluble antigens are rapidly taken up by LSEC and can be cross-presented within 1h ...