E-Dissertationen: Search
Now showing items 1-4 of 4
Pharmacokinetic / Pharmacodynamic Modeling and Simulation of Biomarker Response to Venlafaxine and Sunitinib Administration
(2011-03-23)
In this thesis the concept of pharmacokinetic/pharmacodynamic modeling using biomarkers for the description of concentration-effect relationships was illustrated on the example of two projects with drugs from different ...
From cell to robot: A bio-inspired locomotion device
(2014-05-02)
Bionics or biomimetics is an interdisciplinary research field, a scientific approach to applicate naturally developed biological systems, methods and solutions to the study and design of technology and engineering systems. ...
Application of Sensitive API-Based Indicators and Numerical Simulation Tools to Advance Hot-Melt Extrusion Process Understanding
(2019-09-11)
This dissertation explored the use of active pharmaceutical ingredients (APIs) as indicator substances as well as numerical process simulation to enhance process understanding of hot-melt extrusion (HME) in the pharmaceutical ......
Model-based formulation of amorphous solid dispersions made by hot-melt extrusion
(2019-08-21)
Regarding hot-melt extrusion in early pharmaceutical formulation and process development, techniques and procedures are needed to simplify the application of hot-melt extrusion (HME) and to decrease the effort in terms of ......