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New bioactive metabolites from the marine-derived fungus Dichotomomyces cejpii and their pharmacological relevance
(2015-01-13)
Natural products from fungal sources provide an astonishing diversity of bioactive molecules. The secondary metabolite production in fungi is strongly affected by environmental influences and the isolation of fungal strains ......
Microglial sialic-acid-binding immunoglobulin-like lectin-H (Siglec-H) and Siglec-11 in neuroinflammation
(2015-01-16)
Sialic acid binding Siglecs are involved in various pathological processes. A minor fraction of Siglecs mediates activating signals via the ITAM linked DAP12 adaptor protein while the majority of Siglecs modulates inflammatory ......