E-Dissertationen: Search
Now showing items 1-4 of 4
Gene targeting in human pluripotent cell-derived neural stem cells for the study and treatment of neurological disorders
(2015-11-19)
Modern stem cell technology has made remarkable progress in recent years with the discovery of induced pluripotency, enabling the production of any cell type from any person in unlimited quantities, as well as improved ...
Mechanisms of memory consolidation: Analyzing the coordinated activity of concept neurons in the human medial temporal lobe during waking and sleep
(2018-12-11)
The aim of this thesis is to investigate the role of human concept neurons in memory consolidation during sleep. Memory consolidation is a process by which memories initially dependent on the hippocampus are transferred ...
Mechanisms of action of novel antiepileptic drugs in chronic epileptic hippocampus
(2019-05-21)
Globally, at least 50 million people suffer from epilepsy and almost one third of these do not respond to treatment with one or even multiple antiepileptic drugs (AEDs). One of the most prominent approaches trying to explain ...
Targeting aberrant dendritic integration to treat cognitive comorbidities of epilepsy
(2022-07-07)
Memory deficits are one of the most debilitating and common symptoms of temporal lobe epilepsy. However, so far, little is known about mechanisms underlying cognitive deficits and how pharmacologically target them. In most ...