Aim: The aim of this thesis was the analysis of copy number variations of the mitochondrial DNA (mtDNA) in several tissues and cell types with regard to different mitochondrial associated disorders.
Background: The ...

In der vorliegenden Dissertation werden Stärke und Richtung von Interaktionen zwischen komplexen dynamischen Systemen mit Zellularen Neuronalen Netzen (CNN) erfolgreich charakterisiert. Die Berechnung von Kenngrößen zur ...

The focus of this work was to elucidate the contribution of a single Na⁺ channel a-subunit, namely Na_V1.6, to the discharge properties of CA1 pyramidal neurons. In the first part of this work, we show ...