α-Synuclein is a soluble, cellular protein that in a number of neurodegenerative diseases, including Parkinson's disease, multiple system atrophy, and Lewy body dementia aggregates into pathological protein deposits. ...

The endocannabinoid system has been implicated in the regulation of glial activity and progression of brain ageing. Mice constitutively or specifically lacking the cannabinoid receptor 1 (CB1) on neurons or GABAergic neurons ...