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Simultaneous identification of nucleotide-modified aptamers with different properties by multiplexed click-SELEX
(2020-06-18)
Voltage-gated sodium channels (VGSC) are important key regulators in excitable tissue that initiate and propagate the action potential in specifically excitable tissue such as brain nerves or muscle. In order to understand ...
Selection of an aptamer and development of a genetic device to control mRNA stability in response to light
(2022-02-09)
Artificial autocatalytic RNA molecules, so-called aptazymes, are utilized as genetic devices to study and influence biological processes. These genetic devices consist of the autocatalytic RNA part, the ribozyme, and a ...