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Mechanisms of single-stranded RNA and type I interferon induced suppression of adaptive immune responses
(2010-04-01)
Toll-like receptors (TLRs) belong to the pattern-recognition receptors (PRR) expressed mainly by cells of the innate immune system and recognize conserved structures derived from microbes. Stimulation of TLRs by their ...
Ocular Onchocerciasis: The Role of Toll-Like Receptor-2 and Interferon-γ
(2010-03-17)
River Blindness is still highly prevalent in subsaharan Africa with millions of people suffering from the infection with Onchocerca volvulus. This filarial worm harbors the endosymbiont Wolbachia which was ...