E-Dissertationen: Suche
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Hippocampal cellular and network properties in a mouse model of metachromatic leukodystrophy
(2017-11-30)
The human disease of metachromatic leukodystrophy (MLD) is caused by a single or multiple allelic mutations within the gene locus of arylsulfatase A (ASA). This protein is a lysosomal enzyme catalyzing the degradation of ...
Vergleichende Untersuchung der Genexpression in humanen Tumorzellknoten und Tumorzellrasen in vitro
(2017-03-24)
Während der Arzneimittelentwicklung scheitern viele in vitro vielversprechend scheinende Wirkstoffe während der klinischen Prüfung am humanen Patienten. Für onkologische Wirkstoffe ist die Ausfallquote besonders hoch. Aus ......
The importance of endogenous cannabinoids in stress-related disorders and depression
(2017-02-03)
The endogenous cannabinoid system (ECS) is a unique neuromodulatory system, essentially involved in a variety of physiological processes. It consists of the two major endogenous cannabinoids (eCBs), anandamide and 2-AG, ......