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Advanced population pharmacokinetic modelling to quantify selected characteristics of drugs
(2010-08-03)
The ophthalmic lyophilisate formulation has been known for its safety, tolerability, and ability to achieve higher concentrations of a drug in the internal tissue of the eye compared with the conventional eye drop. Based ...
Characterization of VKORC1L1 with respect to VKORC1
(2019-07-10)
Vitamin K reduction is essential and catalyzed by two enzymes in vitro. Vitamin K 2,3-epoxide reductase complex subunit 1 (VKORC1) reduces vitamin K to sustain γ-carboxylation of vitamin K dependent (VKD) proteins. This ...