Krüppel, Roland: Dendritic integration in hippocampal dentate gyrus granule cells. - Bonn, 2011. - Dissertation, Rheinische Friedrich-Wilhelms-Universität Bonn.
Online-Ausgabe in bonndoc:
author = {{Roland Krüppel}},
title = {Dendritic integration in hippocampal dentate gyrus granule cells},
school = {Rheinische Friedrich-Wilhelms-Universität Bonn},
year = 2011,
month = apr,

note = {Hippocampal granule cells are critical relay stations to transfer spatial information from the entorhinal cortex into the hippocampus proper. Therefore, the integrative properties of the small-caliber granule cell dendrites were examined in this thesis, using a combination of dual somato-dendritic patch-clamp recordings and two-photon glutamate uncaging. These experiments revealed unusual integrative properties that differ substantially from other principal neurons. Due to a strong dendritic voltage attenuation, the impact of individual synapses on granule cell output is low. At the same time, integration is linear, only weakly affected by input synchrony, and is independent of the spatial location of input sites. These integrative properties can enhance contrast in the generation of place-specific firing maps from entorhinal inputs and contribute to the sparse representation of space in the dentate gyrus.},
url = {}

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