Fakultäten der Universität Bonn: Suche
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Phylogeny and evolution of Adephaga and Neuropterida (Insecta: Holometabola) as inferred from analyses of next-generation sequencing data
(2021-09-17)
Knowing the evolutionary relationships of species is fundamental for comparative studies in biology as well as for biodiversity conservation. The main topic of this thesis is the investigation of phylogenetic relationships ...
Funktionelle Untersuchungen des ABC-Transporters ABCG2
(2021-10-15)
Das Phänomen der Multidrug Resistance (MDR) stellt ein bedeutsames Problem bei der Behandlung von Tumoren mit Chemotherapeutika dar. Die ABC-Transporter ABCB1, ABCC1 und ABCG2 sind an der Entstehung der MDR beteiligt. ...
Concepts of Immune Regulation in Chronic Filarial Infections
(2021-04-21)
Despite worldwide efforts to reduce filariasis, over 100 million individuals still suffer from filarial infections. Filarial infections continue to be a substantial drain at both economic and health levels, especially in ......
Electrostatic anchoring of SNAP25 to the plasma membrane
(2021-07-21)
Neurotransmission is based on incredibly rapid membrane trafficking cycles, mediating the release of neurotransmitters. The fusion machinery of the well-studied SNARE protein complex ensures the speed and precision of ...
Bridging between data and knowledge: New ways to better understand Alzheimer's Disease and Type 2 Diabetes comorbidity
(2021-06-15)
The holistic understanding of biological phenomena enabled by systems biology forms the basis of current research. As opposed to the principle of classical biology where behavior of a biological system is explained by ...
Odor-evoked modulation of the olfactory bulb by projections from the horizontal limb of the diagonal band of Broca
(2021-07-09)
Olfactory input encodes essential information about the environment and shapes adapted behavioral reactions. Hence, the olfactory system is complex with diverse brain areas processing the sensory input on different levels. ...
Phenotyping of wheat resistance to Fusarium head blight using hyperspectral imaging
(2021-02-10)
The integrated management of Fusarium head blight (FHB) on wheat depends on the implementation of agricultural practices, cultivation of resistant varieties, and fungicides application. Reducing yield losses and mycotoxin ......
The interplay of differentially γ-carboxylated vitamin K dependent proteins constitute variable VKCFD1 phenotypes
(2021-11-18)
Vitamin K dependent coagulation factor deficiency type 1 (VKCFD1) is a rare hereditary bleeding disorder caused by mutations in γ-Glutamyl carboxylase (GGCX). VKCFD1 patients are treated with high dose of vitamin K, ...
Investigation of Heat Shock Protein 70 and Toll-like Receptor 4 functions during inflammation reaction by mechanical compression in human periodontal ligament cells
(2021-06-24)
Biomechanical forces exerted during treatment with orthodontic appliances cause tensile and compressive strain within the periodontal ligament (PDL) of affected teeth followed by ischemia on the compression side. Further, ...
Detection of Legionella pneumophila and Pseudomonas aeruginosa and biofilm experiments in four different cooling towers (construction and biocide treatment) and evaluation of IDEXX most probable number methods in industrial water samples
(2021-11-30)
The responsible maintenance of evaporative cooling systems is an essential element in reducing the risk of the environmental dispersion of legionellae and Legionnaires’ disease outbreaks. In Germany, the 42nd Ordinance ......