Faculties of University Bonn: Search
Now showing items 651-660 of 730
Particle engineering for high dose dry powder inhalation of itraconazole
(2022-12-05)
Itraconazole (ITZ) is considered as first-line therapy against respiratory infections such as allergic bronchopulmonary aspergillosis. Local treatment of these infections is regarded beneficial as it might reduce systemic ...
Loss of Profilin3 Impairs Spermiogenesis by Affecting Acrosome Biogenesis, Autophagy, Manchette Development and Mitochondrial Organization
PFN4 is Required for Acrosome Biogenesis by Regulating Autophagy through PI3K/AKT/mTOR Pathway
(2022-12-02)
Loss of Profilin3 Impairs Spermiogenesis by Affecting Acrosome Biogenesis, Autophagy, Manchette Development and Mitochondrial Organization
Profilins (PFNs) are key regulatory proteins for the actin ......
PFN4 is Required for Acrosome Biogenesis by Regulating Autophagy through PI3K/AKT/mTOR Pathway
Profilin4 (Pfn4) is a member of profilin gene family and during spermiogenesis localizes to the ......
Profilins (PFNs) are key regulatory proteins for the actin ......
PFN4 is Required for Acrosome Biogenesis by Regulating Autophagy through PI3K/AKT/mTOR Pathway
Profilin4 (Pfn4) is a member of profilin gene family and during spermiogenesis localizes to the ......
GLOSTAR: Investigating Tracers of Early High-Mass Star Formation
(2023-05-12)
High-mass stars (>8 msol) are not as numerous as their less massive counterparts but have a much more profound impact on their environment within their native galaxies. Despite their importance, our understanding of their ...
Neuroanatomie und Funktionsmorphologie Peripherer Rezeptorneurone mit Direkten Projektionen in das Protocerebrum des Insektengehirns
(2023-04-20)
Zur Wahrnehmung unterschiedlicher thermischer Reize hat sich bei Insekten eine Reihe von Thermorezeptoren entwickelt. Der pyrophile („feuerliebend“) „Australische Feuerkäfer“ (Merimna atrata) besitzt paarige Infrarot-(IR)-Organe ......
Symptom burden in cancer patients: Evaluation of medication risks and development of disease-specific PRO instruments
(2023-04-27)
In oncology, adverse events are usually documented using the Common Terminology Criteria for Adverse Events (CTCAE). This physician-reported assessment can be supported by patient-reported outcomes (PRO) that play an ...
Interesse an Insekten fördern: Eine Design-Based Research Studie mit Jugendlichen
(2023-02-23)
Um den Herausforderungen des Rückgangs von Insekten zu begegnen ist es von Bedeutung, das Interesse an Insekten zu fördern. Interesse ist eine wichtige Lernvoraussetzung und zentral für die Bereitschaft, Biodiversität zu ...
Endocannabinoid system and the aging locus coeruleus
(2022-11-28)
The locus coeruleus (LC) is a small nucleus located in the pons of the brainstem, representing the major source of noradrenaline (NE) in the central nervous system. Although the LC consists of a relatively low number of ...
Identification of Pharmacogenomic and Functional Biomarkers for Antidepressant Treatment Outcome in Patients-Derived Lymphoblastoid Cell Lines
(2023-03-29)
Major depression is the most prevalent mental disorder worldwide. Pharmacological management of the disease is considered a cornerstone in treatment guidelines adopted by many industrialized countries. However, response ...
Pharmacometric modeling of fluoropyrimidines
(2023-03-07)
The fluoropyrimidine drugs fluorouracil (5FU) and capecitabine are widely used for the treatment of various solid tumors. Despite the long-term clinical experience with these drugs a substantial proportion of patients is ...
Unconscious manipulation of human diet-related behaviors by the internal and external environment
(2022-11-22)
Study I: Manipulated by Marketing and Hormones? The relevance of Oxytocin for Marketing Placebo Effects on Food Product Perception
What consumers expect from food products and how they experience ...
What consumers expect from food products and how they experience ...