Development of protein loaded microparticles and nanoparticles for antigen delivery
Development of protein loaded microparticles and nanoparticles for antigen delivery
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dc.contributor.advisor | Lamprecht, Alf | |
dc.contributor.author | Francis, Donny | |
dc.date.accessioned | 2020-04-20T04:13:06Z | |
dc.date.available | 2020-04-20T04:13:06Z | |
dc.date.issued | 12.12.2014 | |
dc.identifier.uri | https://hdl.handle.net/20.500.11811/6210 | |
dc.description.abstract | An innovative approach of developing modern adjuvants is the design of particulate antigen delivery systems. These, typically polymeric, particles that are in a size range of micro- and nanoparticles can be used as drug carrier systems. Such drug carriers can target antigen presenting cells, which is crucial for long-lasting immunity. The aim of this work was the development and characterization of polymeric micro- and nanoparticles for the antigen delivery using biodegradable and biocompatible polymers. In this work poly(D,L-lactide-co-glycolide) (PLGA) was used as a polymer, because PLGA-microparticles and PLGA-nanoparticles already showed a potential to be used as vaccine adjuvants. | |
dc.language.iso | eng | |
dc.rights | In Copyright | |
dc.rights.uri | http://rightsstatements.org/vocab/InC/1.0/ | |
dc.subject.ddc | 500 Naturwissenschaften | |
dc.title | Development of protein loaded microparticles and nanoparticles for antigen delivery | |
dc.type | Dissertation oder Habilitation | |
dc.publisher.name | Universitäts- und Landesbibliothek Bonn | |
dc.publisher.location | Bonn | |
dc.rights.accessRights | openAccess | |
dc.identifier.urn | https://nbn-resolving.org/urn:nbn:de:hbz:5n-38473 | |
ulbbn.pubtype | Erstveröffentlichung | |
ulbbnediss.affiliation.name | Rheinische Friedrich-Wilhelms-Universität Bonn | |
ulbbnediss.affiliation.location | Bonn | |
ulbbnediss.thesis.level | Dissertation | |
ulbbnediss.dissID | 3847 | |
ulbbnediss.date.accepted | 21.11.2014 | |
ulbbnediss.institute | Mathematisch-Naturwissenschaftliche Fakultät : Fachgruppe Pharmazie / Pharmazeutisches Institut/Pharmazeutische Technologie | |
ulbbnediss.fakultaet | Mathematisch-Naturwissenschaftliche Fakultät | |
dc.contributor.coReferee | Wagner, Karl Gerhard |
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