The Faculty of Medicine: Medizinische Fakultät: Recent submissions
Now showing items 181-200 of 2232
-
Schistosomiasis endemicity and its role in sexually transmitted infections: A systematic review and meta-analysis
(2024-09-02)<strong>Introduction:</strong> Schistosomiasis, a tropical parasitic disease, affects 779 million people globally, with 85% of cases in Africa. The interplay between schistosomiasis and other sexually transmitted infections ... -
Therapeutic alliance in individual adult psychotherapy: A systematic review of conceptualizations and measures for face-to-face- and online-psychotherapy
(2024-06-27)<strong>Background:</strong> The therapeutic alliance (TA) is a robust and pantheoretical predictor of treatment outcome in Face-to-Face- (F2F-) and Online-psychotherapy (Online-PT). Many authors have proposed several ... -
Auswirkung der Lagerungsdauer von Erythrozytenkonzentraten auf den Anstieg der Hämoglobin-Konzentration nach Transfusion: Eine Subgruppen-Analyse der LIBERAL-Studie
(2025-08-01)Die LIBERAL-Studie ist eine DFG geförderte, prospektive, randomisierte, multizentrische, kontrollierte, klinische Phase-IV-Studie, an der 2.470 ältere Patienten teilnehmen, die sich einer nicht-herzchirurgischen Operation ... -
Investigating the Role of Descending Neurons in Freely Flying Drosophila melanogaster
(2025-08-01)Understanding how neural circuits generate complex behaviors remains a central challenge in neuroscience. This thesis investigates the neural basis of flight control in <em>Drosophila melanogaster</em>, focusing on how ... -
Prädiktoren für eine behandlungsbedürftige Koronarstenose nach einer ventrikulären Arrhythmie bei Patienten mit Implantierbarem Kardioverter-Defibrillator (ICD)
(2025-08-01)In dieser retrospektiven Studie wurden 183 ICD-Patienten untersucht, die nach einer ventrikulären Arrhythmie (VA) eine Koronarangiographie erhielten. Ziel war es, Prädiktoren für das Vorliegen einer behandlungsbedürftigen ... -
Neuroprotective Role and Immunomodulatory Effects of Sialylation
(2025-07-29)Sialic acids are terminal sugars on the cellular glycocalyx, crucial for modulating immune responses in the sialylated central nervous system. Sialylation acts as an inhibitory checkpoint, regulating inflammation and tissue ... -
Force system of 3D-printed orthodontic aligners made of shape memory polymers: An in vitro study
(2024-06-10)This study aimed to report forces and moments delivered by 3D-printed aligners. Tera Harz TC-85 resin and Zendura FLX (ZF) thermoformed sheets (0.76 mm) were used. Rectangular strip specimens (50 × 10 × 0.6 mm) were produced ... -
Effect of the Height of a 3D-Printed Model on the Force Transmission and Thickness of Thermoformed Orthodontic Aligners
(2024-06-20)This research aims to investigate the influence of model height employed in the deep drawing of orthodontic aligner sheets on force transmission and aligner thickness. Forty aligner sheets (Zendura FLX) were thermoformed ... -
Retro Mode Imaging for Detection and Quantification of Sub-RPE Drusen and Subretinal Drusenoid Deposits in Age-Related Macular Degeneration
(2024-07-15)<strong>Background:</strong> Drusen and drusenoid deposits are a hallmark of age-related macular degeneration (AMD). Nowadays, a multimodal retinal imaging approach enables the detection of these deposits. However, ... -
Diagnoses and Treatment Recommendations—Interrater Reliability of Uroflowmetry in People with Multiple Sclerosis
(2024-07-18)Background: Uroflowmetry (UF) is an established procedure in urology and is recommended before further investigations of neurogenic lower urinary tract dysfunction (NLUTD). Some authors even consider using UF instead of ... -
The Phenotypic Correlates and Genetic Basis of the Central Neuroendocrine System
(2025-07-29)The hypothalamus is considered the body’s principal center for maintaining homeostasis and orchestrating the secretion of multiple hormones. The pineal gland closely interacts with the hypothalamus and forms an essential ... -
Vergleich des Randschlussverhaltens von DeltaFil, einem neuartigen Glasionomerzement, mit herkömmlichen Restaurationsmaterialien in Klasse-II-Kavitäten: Eine in-vitro-Untersuchung nach künstlicher Alterung
(2025-07-29)Ziel dieser in-vitro-Studie war es, das Randspaltverhalten von DeltaFil, einem neu entwickelten Glasionomerzement der Firma DMG, im Vergleich zu herkömmlichen Restaurationsmaterialien in Klasse-II-Kavitäten zu untersuchen. ... -
Extracellular matrix substrates differentially influence enteric glial cell homeostasis and immune reactivity
(2024-07-25)<strong>Introduction:</strong> Enteric glial cells are important players in the control of motility, intestinal barrier integrity and inflammation. During inflammation, they switch into a reactive phenotype enabling them ... -
In vitro extracellular replication of Wolbachia endobacteria
(2024-07-18)Obligate intracellular endobacteria of the genus <em>Wolbachia</em> are widespread in arthropods and several filarial nematodes. Control programs for vector-borne diseases (dengue, Zika, malaria) and anti-filarial therapy ... -
Bidirectional Effect of Long-Term Δ9‑Tetrahydrocannabinol Treatment on mTOR Activity and Metabolome
(2024-08-14)Brain aging is associated with cognitive decline, reduced synaptic plasticity, and altered metabolism. The activity of mechanistic target of rapamycin (mTOR) has a major impact on aging by regulating cellular metabolism. ... -
Assessment of local sensitivity in incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) lesions in intermediate age-related macular degeneration (iAMD)
(2024-07-09)<strong>Objective</strong> Lesions of incomplete retinal pigment epithelium and outer retinal atrophy (iRORA) are associated with disease progression in intermediate age-related macular degeneration (AMD). However, the ... -
Placental Sonomorphologic Appearance and Fetomaternal Outcome in Fontan Circulation
(2024-09-01)<strong>Objectives:</strong> Pregnancies in women with Fontan circulation are on the rise, and they are known to imply high maternal and fetal complication rates. The altered hemodynamic profile of univentricular circulation ... -
The role of RER1 in the assembly and transport of TREM2-DAP12 complex and cellular lipid metabolism
(2025-07-25)DNAX-activating protein of 12 kDa (DAP12) is a transmembrane adapter protein expressed on lymphoid and myeloid lineage cells, and interacts with several immune receptors to form functional complexes that trigger intracellular ... -
Modelling structure-function relationships from neurons to networks in the cerebral cortex
(2025-07-24)Using a multi-scale model based on extensive experimental data, I explored structure-function relationships in cortex. At a macro-scale, I used ANNs with cortical features to show that sparse connectivity enables efficient ... -
Targeting tumor cells with cytokine-induced killer cells and bifunctional peptides
(2025-07-23)Antimicrobial peptides have gained much attention in clinical research due to their extensive possibilities of application beyond antimicrobial use. The modification of antimicrobial peptides enables the peptides to target ...
