Mathematisch-Naturwissenschaftliche Fakultät: Suche
Anzeige der Dokumente 121-130 von 220
Verbesserung der Befundinterpretation bei forensisch-toxikologischen Fragestellungen am Beispiel von Prothipendyl, Cannabinoiden und neuen psychoaktiven Substanzen: Bedeutung von Metaboliten und Referenzdaten
(2020-01-06)
Für eine umfassende forensisch-toxikologische Interpretation von Substanznachweisen in biologischen Matrizes bedarf es einer fundierten Datenlage. Neben pharmakologischen bzw. toxikologischen Eigenschaften der Substanzen ...
Development of workflows for metabarcoding of mass-samples: A case study on Diptera
(2020-02-14)
The main goal was developing a workflow for comprehensive biodiversity monitoring using a DNA Barcoding approach. As one of the major insect groups in the Palearctic the diverse order of Diptera served as an experimental ...
Climate field reconstructions from pollen and macrofossil syntheses using Bayesian hierarchical models
(2020-01-09)
Studying past climate states is important to understand climate changes and climate variability on centennial to orbital timescales, to analyze the reaction of the Earth system to large-scale changes in external forcings, ...
Pulsar searching with the Effelsberg telescope
(2020-02-21)
Pulsars, highly magnetised rapidly-rotating neutron stars, have proved themselves to be incredible tools for exploring many aspects of fundamental physics and astrophysics. More opportunities for building new theories and ...
Probing new physics with boosted H → bb decays with the ATLAS detector at 13 TeV
(2020-01-27)
The discovery of the Higgs boson by the ATLAS and CMS collaborations at the Large Hadron Collider was a major success in particle physics. Even though studies of the Higgs boson suggest that its properties are in agreement ......
The chloroplast calcium sensor protein CAS is part of the STN7/STN8 kinase phosphorylation network and is required for photoacclimation
(2020-03-10)
In the present work, the phosphorylation profile of the chloroplast-localized Calcium Sensing Receptor (CAS) from A. thaliana was investigated and it could be shown that CAS is a target of multiple protein kinases acting ......
Development of oligomer-specific antibodies against tau protein and testing of therapeutic potential in a cell model of tau pathology
(2020-04-15)
Tau, a microtubule associated protein, forms abnormal aggregates in many neurodegenerative diseases such as Alzheimer disease (AD). There is an urgent need for disease-modifying therapies of AD and related tauopathies. ......
Regulation des Cochaperons BAG3 durch Phosphorylierung und Dephosphorylierung
(2020-01-07)
Die Zelle ist die kleinste Organisationseinheit, aus der alle Organismen aufgebaut sind. Sie ist auf ein Gleichgewicht der Proteinausstattung, die Proteostase, angewiesen. Auch das Cytoskelett ist essentiell für die Zelle, ...
Towards Semantic Integration of Supply Chain and Production Data
(2020-11-06)
Data is a critical ingredient for many analyses. Its recent exponential growth allowed utilizing computers to solve previously considered hard problems. For organizations and entire economies, being able to solve harder ...
Untersuchungen zur Synthese und Reaktivität 1,3-ambiphiler Phosphinidenoidkomplexe mit einem P-O-Element-Strukturmotiv
(2020-05-05)
Die Arbeit behandelt Untersuchungen zur Darstellung neuartiger 1,3-ambiphiler Phosphinidenoidkomplexe, welche neben dem Phosphoratom als Donorfunktion entweder ein Bor- oder ein Siliziumatom als Akzeptorfunktion aufweisen. ...