The Faculty of Mathematics and Natural Sciences: Search
Now showing items 1101-1110 of 1166
The chromatin organizer Satb1 regulates the differentiation into CD4+ TH subsets and is essential for the development of TH17 cells
(2021-06-04)
CD4+ T cells play a critical role in host defense and tissue homeostasis. Upon encountering their specific antigen, naive CD4+ T cells can differentiate into the effector T helper (TH) subsets ...
Permissive and decisive roles of Hox code genes in limb induction
(2022-08-15)
Vertebrates display positional identities along the head-to-tail axis. The forelimb is one of the characteristics among them that shows its specific position at the interface between the cervical and thoracic region ...
Biodiversity and chemical ecology of selected gastropods from Iran, Persian Gulf
(2024-02-07)
Marine gastropods exhibit unique adaptations to marine environments have become a subject of interest in evolutionary biology. This study unveils Peronia persiae Maniei, Espeland, Mohavedi & Wägele, 2020, a new species of ......
pH Regulation in Human Sperm
(2024-01-18)
In the female reproductive tract, sperm undergo a maturation process, called capacitation, which enables sperm to fertilize the oocyte. The complex cellular mechanisms underlying capacitation are not well understood. Besides ...
Enzymatische Herstellung und Reinigung von Fructooligosacchariden des Inulin-Typs und deren Verwertung durch abundante Darmbakterien
(2024-01-24)
Fructooligosaccharide vom Inulin-Typ (I-FOS) sind präbiotische Fructan-Oligomere, die hauptsächlich aus ß-(2,1)-verknüpften Fructose-Einheiten bestehen. I-FOS haben aufgrund ihrer gesundheitsfördernden Wirkung und funktionellen ......
Das Cyclodepsipeptid FR900359: Ein Insektizid mit neuem Wirkmechanismus aus Cand. Burkholderia crenata und Chromobacterium vaccinii
(2024-01-16)
Sekundärmetabolite (SM) sind für ihr breites Spektrum an Bioaktivitäten bekannt und daher eine wichtige Quelle für neue Arzneimittelkandidaten. Neben ihrer Relevanz für die Therapie von Erkrankungen sind SM und ihre ......
The cyclic depsipeptide FR900359: An insecticide with a novel mode of action from Cand. Burkholderia crenata and Chromobacterium vaccinii
Secondary metabolites (SM) are known for their broad spectrum ......
The cyclic depsipeptide FR900359: An insecticide with a novel mode of action from Cand. Burkholderia crenata and Chromobacterium vaccinii
Secondary metabolites (SM) are known for their broad spectrum ......
Molecular Mechanisms of Aβ Peptide Aggregation and Interaction with Microglia via TREM2
(2024-01-22)
Alzheimer’s disease (AD) is a progressive neurodegenerative disorder accompanied by a decline in cognitive functions. It is estimated that roughly 50 million people are currently suffering from AD, a number that is thought ...
Cilia-dependent signaling pathways controlling adipose tissue plasticity
(2022-11-15)
Primary cilia serve as cellular antennae that detect extracellular signals and transduce this information into an intracellular response. Dysfunction of primary cilia leads to a range of severe diseases, i.e., the ......
Primäre Zilien dienen als zelluläre Antenne, welche extrazelluläre Signale detektieren und eine zelluläre Reaktion hervorrufen. Dysfunktionale primäre Zilien rufen eine Reihe an schwerwiegenden Erkrankungen hervor, wie das ......
Primäre Zilien dienen als zelluläre Antenne, welche extrazelluläre Signale detektieren und eine zelluläre Reaktion hervorrufen. Dysfunktionale primäre Zilien rufen eine Reihe an schwerwiegenden Erkrankungen hervor, wie das ......
Danger signaling pathways in aortic disease
(2024-02-19)
The aorta connects the heart to the peripheral circulation and organs. It is necessary for the regulation of hemodynamics and therefore, aortic disease affects all organs and the survival of the individual. In aortic valve ...
Optogenetische Stimulation des nativen Herzmuskels durch Adeno-assoziierte Virustransduktion von Channelrhodopsin-2
(2022-12-15)
Die Optogenetik ist eine innovative Methode, die die transgene Expression von lichtsensitiven Proteinen verwendet zur elektrophysiologischen oder biochemischen Stimulation von Zellen durch Beleuchtung. Das Beleuchten mit ......