The Faculty of Mathematics and Natural Sciences: Search
Now showing items 101-110 of 159
Pattern Recognition Receptor and Vaccination Studies in the Murine Model of Lymphatic Filariasis
(2013-03-06)
Lymphatic filariasis is a parasitic helminth infection that affects approximately 120 million people. About one third of the infected individuals develop pathological manifestations, e.g. lymphedema. Causative agents of ......
Rapid astrocyte morphology changes during epileptogenesis in the rodent hippocampus
(2017-05-15)
In the past decades astrocytes have been demonstrated to play an important role in physiological brain processes but also neurodegenrative diseases. Their characteristic morphology allows them to closely contact neurons. ...
Unravelling mechanisms causing astrocytic uncoupling in epilepsy
(2017-10-06)
The dynamic regulation of connexins throughout its life cycle has profound impact on the level of gap junctional coupling in astrocytes. Astrocytic uncoupling in epilepsy can be viewed in the context of modifications in ...
Organization and function of signaling molecules in sperm
(2017-09-15)
Successful fertilization depends on the ability of sperm to locate the egg. Sperm from different species rely on diverse signaling components to gather chemical and physical cues and transduce them into a behavioral swimming ......
Um die Eizelle zu befruchten, müssen die Spermien die Eizelle zunächst lokalisieren. Dabei helfen ihnen unterschiedliche chemische oder physikalische Signale auf dem Weg zur Eizelle, die dann das Schwimmverhalten der ......
Um die Eizelle zu befruchten, müssen die Spermien die Eizelle zunächst lokalisieren. Dabei helfen ihnen unterschiedliche chemische oder physikalische Signale auf dem Weg zur Eizelle, die dann das Schwimmverhalten der ......
Peroxin3, a newly identified regulator of melanocyte development and melanosome biogenesis in zebrafish Danio rerio
(2017-04-20)
Previous efforts aimed to understand the consequences of a dysregulated control of peroxisome biogenesis and of the dynamics of peroxisomal matrix proteins. Nevertheless, previous publications did not fill the existing gap ...
Medium-chain fatty acid metabolism in hepatocytes and adipocytes
(2017-04-11)
Fatty acids (FAs), in free form or incorporated into complex lipids, constitute an inseparable part of the daily human diet. Different carbon atom chain length and saturation rate leads to a huge variety of FAs of which ...
Action of zona pellucida glycoproteins in mouse and human sperm
(2017-08-22)
For fertilization, sperm have to penetrate the oocyte’s vestment, the zona pellucida (ZP). In mouse and human, the ZP consists of three or four different ZP glycoproteins, respectively. Binding of sperm to ZP glycoproteins ...
Transmission of pathogenic α-synuclein to mice
(2017-09-01)
α-Synuclein is a soluble, cellular protein that in a number of neurodegenerative diseases, including Parkinson's disease, multiple system atrophy, and Lewy body dementia aggregates into pathological protein deposits. ...
Maligne Transformation gingivaler Epithelzellen durch Porphyromonas gingivalis
(2017-09-08)
Ziel der vorliegenden Arbeit war es, neue Erkenntnisse einer bakteriell-induzierten chronischen Entzündung (Parodontitis) in Bezug auf eine orale Tumorgenese zu gewinnen. Dazu wurde der Einfluss des parodontopathogenen ......
Sorting, missorting and spreading of Tau in neurons studied in microfluidic chambers
(2017-09-04)
Tau is a microtubule-associated protein which plays an important role in stabilizing microtubules (Mandelkow and Mandelkow, 2012). Tau is mainly an axonal protein but it is missorted into the somatodendritic compartment ...