Mathematisch-Naturwissenschaftliche Fakultät: Suche
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Converting the elusive G protein-coupled adenosine A3 receptor into a highly-stable, well-characterized receptor model for structural studies
(2023-03-06)
The G protein-coupled adenosine A3 receptor (A3AR) is widely expressed in the human body, with the highest expression levels found in lung and liver. The receptor is involved in a number of pathological processes, e.g., ...
Analysis of reprogramming-associated alterations using an isogenic human stem cell system
(2022-03-04)
Human induced pluripotent stem cells (iPSCs) could provide a valuable tool for the production of specific somatic cell types for disease modeling or cell replacement. Considering the molecular complexity of the reprogramming ...
Identification of Genetic Risk Variants for the Development of Gastric Adenocarcinoma
(2023-03-07)
Gastric cancer (GC) is a clinically heterogeneous and one of the most common malignant tumour entities affecting the human gastrointestinal tract with a multifactorial aetiology. Beside environmental risk factors, also ...
Maßgeschneiderte nutzbarkeitserhaltende Pseudonymisierung: Anforderungen, Beschreibung, Umsetzung
(2023-01-30)
Die Verarbeitung personenbezogener Daten ist omnipräsent. Um die Privatsphäre und die informationelle Selbstbestimmung der Betroffenen zu achten, ist das Ergreifen von Maßnahmen zum Schutze der Vertraulichkeit der Daten ...
Theoretical and Practical Aspects of Finite Closure Systems for Mining and Learning
(2023-10-04)
This thesis investigates the potential and limitations of different adaptations of half-space separations in ordinary Euclidean spaces, one of the most popular paradigms in machine learning, to abstract finite closure ...
Adapting OpenCourseWare Based on the Needs and Preferences of Disabled Learners
(2022-12-22)
OpenCourseWare (OCW) systems are becoming a significant source of learning that are widely used for various educational purposes. With the COVID-19 Pandemic situation, these resources showed the impact of having material ...
Modifikationen von Anwendungen, Konformationen und Selektivitäten von Titanocenen
(2023-03-16)
(noch nicht zugänglich / not yet accessible)
Investigation Towards the Total Synthesis of Portentol via an Inverse Electron Demanding Diels Alder Reaction and Studies Towards the Total Synthesis of Brevistin
(2024-03-25)
(noch nicht zugänglich / not yet accessible)
Development of Molecular Chimeras Targeting the NLRP3 Inflammasome and HDAC6
(2024-03-28)
(noch nicht zugänglich / not yet accessible)
Approximations for Hierarchical and Lower-Bounded Clustering and the Complexity of Minimum-Error Triangulation
(2024-03-28)
Clustering deals with the problem of finding structures in data. Given a number k we search for a good partition of a set of data points into at most k sets, where the sets of the partition are called clusters. In the ...