The Faculty of Mathematics and Natural Sciences: Search
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Versatile Trityl Radicals: Improving Applications via Tailored Synthesis
(2021-06-30)
Generally, organic radicals are considered as rather unstable and highly reactive species that are just intermediates of chemical reactions.
However, this paradigm was disproved already in 1900 my Moses Gomberg, ...
However, this paradigm was disproved already in 1900 my Moses Gomberg, ...
Influence of High-Pressure Compaction of Binary Mixtures on Solubility, Dissolution and Wettability of Borderline Poorly Soluble Drugs Employing Standard Excipients
(2021-12-14)
Many of new drug candidates are impaired by low aqueous solubility and slow dissolution rates, which may hinder their pharmacological response. Therefore, there is an increasing need to investigate and implement new ...
Far-infrared-to-centimeter-wave spectroscopicobservations of Planck-selected starburst galaxies
(2021-03-15)
Star-formation processes in the early Universe have had a dramatic influence on the further development of galaxies. The peak era for stellar production occurred in early cosmic times, and most of the stars that could have ......
Investigation of the in vivo Lysosomal Proteome Changes in Different Starvation Periods
(2021-04-09)
Nutrient deprivation can change the activity and subcellular localization of a protein. The cellular response to starvation includes the autophagy/lysosomal degradation pathway and the nutrient signaling pathway via the ......
External Control of Many-Body Quantum Systems
(2021-10-05)
In strongly correlated many-body quantum systems, the complex interplay between a large number of degrees of freedom and the presence of various competing energy scales leads to rich phase diagrams, but also renders these ...
Synthese und Reaktionen von phosphorfunktionalisierten 1,3-Dithiol-2-thionen
(2021-01-05)
Die Dissertation "Synthese und Reaktionen von phosphorfunktionalisierten 1,3-Dithiol-2-thionen" beschreibt die Darstellung von tricyclischen 1,4-Dihydro-1,4-diphosphininen, die 1,3-Dithiol-2-thion-Einheiten tragen. Zugleich ...
Biochemical characterization of the human Cyclin-dependent kinases Cdk7 and Cdk10
(2021-08-13)
Protein kinases comprise a large superfamily of enzymes regulating a plethora of cellular processes. Dysregulation of protein kinases, such as loss of activity, hyperactivity or mislocalisation, is often accompanied with ...
Development of Computational Methods for Rationalizing Chemical Lead Optimization and Compound Design
(2021-09-22)
Chemical lead optimization (LO) plays an important role in pharmaceutical drug discovery. It represents a highly complex multi-objective process, in which the ultimate goal is to identify a suitable candidate molecule that ...
Role of innate lymphoid cells in type 1-dominated experimental Plasmodium berghei ANKA and type 2-dominated Litomosoides sigmodontis infection
(2021-10-27)
Malaria and filariasis remain among the biggest health problems in the tropics and subtropics, especially in Africa, and in the case of malaria among the ten most frequent causes of death. The parasites that cause malaria ......
The Hubbard Model on the Honeycomb Lattice with Hybrid Monte Carlo
(2021-11-09)
We take advantage of recent improvements in the grand canonical Hybrid Monte Carlo (HMC) algorithm, to perform a precision study of the single-particle gap in the hexagonal Hubbard model, with on-site electron-electron ...