Mathematisch-Naturwissenschaftliche Fakultät: Suche
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CD8 T cell responses during primary and secondary influenza infection - Role of MHC-I expression on non-immune cells
(2021-09-03)
Influenza infection results in strong immune responses in the lung usually leading to clearance of infection and, in some cases, immune pathology with varying degrees of prognosis. CD8 T cells are believed to be one of the ...
The Role of NMDA Receptor Co-Agonists in Dendritic Integration
(2021-03-26)
The integration of synaptic inputs is the fundamental function of neurons. This integration does not only take place at the soma, but also dendrites can actively shape the input-output computations of a neuronal network. ...
Global Timing Optimization in Chip Design
(2021-04-12)
In this thesis, we aim at solving the interconnect optimization problem comprehensively. By balancing global timing, routing, placement, and power constraints in a global model, we obtain solutions which outperform the ...
Mapping the immune landscape in the alveolar space reveals alterations of multiple macrophage states in chronic obstructive pulmonary disease
(2021-03-26)
Chronic obstructive pulmonary disease (COPD) is ranked among the three leading causes of death worldwide and hence constitutes a significant burden, both medically and financially. The disease is characterized by a poorly ...
Geometric and topological recursion and invariants of the moduli space of curves
(2021-10-29)
A thread common to many problems of enumeration of surfaces is the idea that complicated cases can be recovered from simpler ones through a recursive procedure. Solving the problem for the simplest topologies and expressing ...
Structural aspects of the plasmalemmal Amyloid Precursor Protein cluster
(2021-11-12)
Alzheimer’s Disease (AD) is a major socio-economic threat to health care systems and society in general. Involvement of the amyloid-beta peptide (Aβ) and its parent, the amyloid precursor protein (APP), in AD seemed obvious ...
Quantenchemische Untersuchung der elektronischen Eigenschaften von Ferriten
(2021-06-21)
Die vorliegende Arbeit befasst sich mit der theoretischen Untersuchung der optischen und elektronischen Eigenschaften von Spinell-Ferriten MFe2O4 mit M = Mg, Sc, Ti, V, Cr, Mn, Fe, Co, Ni, Cu, Zn und ......
On Discrete and Geometric Firefighting
(2021-08-19)
Wildfires ravaging forests around the globe cost lives, homes and billions in damages every year, which motivates the study of effective firefighting. In the area of theoretical computer science, several different models ......
Design and Development of Depleted Monolithic Active Pixel Sensors with Small Collection Electrode for High-Radiation Applications
(2021-09-27)
Depleted monolithic active pixel sensors (DMAPS) have emerged as a low material and low cost alternative to the established hybrid technology. In this thesis, two large scale prototype chips that feature a fast column-drain ...
Knowledge Context for Entity and Relation Linking
(2021-10-28)
Knowledge graphs (KGs) are structures that provide a compendious representation of real world facts about entities and their relationships. The last decade has seen an increase in the number, size and application of knowledge ...