Natural product chemistry and biosynthetic studies of secondary metabolites from the marine-derived fungus Stachylidium sp.

Abstract

The fungal kingdom has made considerable contributions to the production of peptide secondary metabolites, many of them with therapeutic potential, e.g. the immunosuppressant cyclosporine and the antifungal echinocandins. <br /> The detailed investigation of the marine-derived fungus Stachylidium sp. was the main purpose of this research, which focused on the isolation, structural elucidation and biosynthesis of novel cyclic peptides.