bonndoc - Der Publikationsserver der Universität Bonn: Recent submissions
Now showing items 1-20 of 10958
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Untersuchungen zur Darstellung und Reaktivität von σ3λ3-Oxaphosphiranen
(2025-01-17)Im Rahmen der vorliegenden Arbeit wurde die Freisetzung von σ<sup>3</sup>λ<sup>3</sup>-Oxaphosphiranliganden aus <em>P</em>-CPh<sub>3</sub>-substituierten Oxaphosphiranmetallkomplexen untersucht. Des Weiteren wurde die ... -
Modelling Secondary Circulation in Convective Boundary Layer Using Large Eddy Simulation
(2025-01-17)Mesoscale secondary circulations, which frequently arise over heterogeneous land surfaces, profoundly influence atmospheric structure and characteristics. Its structure is primarily shaped by the combined effects of wind ... -
TCAD Simulations and Test Beam Characterization of MAPS for Future Lepton Colliders
(2025-01-17)Monolithic active pixel sensors (MAPS) produced in a 65 nm CMOS imaging technology are being investigated for applications in particle physics. The MAPS design has a small collection electrode with an input capacitance of ... -
Investigating the Biosynthesis of G Protein Inhibitor FR900359
(2025-01-17)FR900359 (FR) is a potent and selective inhibitor of Gq proteins, obstructing intracellular signaling of numerous G protein-coupled receptors (GPCRs). This makes it a promising pharmacological tool for investigating ... -
Study of B → π ℓ ν and B → ρ ℓ ν decays and extraction of |Vub| at Belle II
(2025-01-16)This thesis presents a measurement of the Cabibbo-Kobayashi-Maskawa (CKM) matrix element magnitude |<em>V<sub>ub</sub></em>| from a simultaneous study of the semileptonic decays <em>B<sup>0</sup> → π<sup>-</sup> ℓ<sup>+</sup> ... -
Root trait response to drought, recovery, and P deficiency of upland rice
(2025-01-16)Phosphorus deficit and intermittent drought can cause high-yield reductions in rice (Oryza sativa L.) production. Large differences in tolerance of low P availability and drought resilience were found in the upland rice, ... -
Blutplasmabestimmung von Brivaracetam, Lacosamid und Perampanel: Behandlungsrelevanz für Epilepsiepatienten
(2025-01-16)Anfallssuppressive Medikamente stellen die Basistherapie von Epilepsiepatienten dar. Ob die Bestimmung der Wirkstoffspiegel dazu beiträgt, die klinische Wirksamkeit zu verbessern und Nebenwirkungen zu vermeiden, ist bisher ... -
Hämodynamische und renale Wirkung des Urotensin II-Rezeptor-Antagonisten Palosuran bei Ratten mit sekundärer biliärer Zirrhose
(2025-01-16)Die führende Rolle in der Entstehung des portalen Hypertonus bei Leberzirrhose nimmt die splanchnische Vasodilatation ein. Trotz der kompensatorischen Aktivierung vasoaktiver Systeme wie zum Beispiel des Renin-Angiotensi ... -
From Comments to Cognition: How online comments on social media influence personal opinion
(2025-01-16)Social media has become central in our daily life, serving both as a mean of interpersonal connection and as a primary source of news consumption. This doctoral dissertation investigates the behavioral and neuroimaging ... -
DNA-Methylierung der FGF-Rezeptoren hinsichtlich der mRNA-Expression, Amplifikation und Sensitivität für Inhibitoren in Plattenepithelkarzinomen der Lunge
(2025-01-14)Während zielgerichtete Therapien beim Adenokarzinom der Lunge inzwischen erfolgreich routinemäßig angewendet werden, sind die klinischen Ergebnisse beim LUSC ernüchternd. Ein Grund hierfür könnte eine ungenügende ... -
Analyse der hämodynamischen Reaktion auf die hypertherme intraoperative Chemoperfusion: Eine deskriptive Studie
(2025-01-14)Die Erhaltung des physiologischen Grundzustandes eines operierten Menschens während einer Operation ist die Hauptaufgabe des Anästhesieteams. Ein wichtiges Element ist dabei die Hämodynamik. Diese muss während eines ... -
Importance of root-soil contact conditions for the microbiota in the soil-rhizosphere-plant continuum
(2025-01-14)The contact zone between a root and the surrounding soil mediates processes such as nutrient and water uptake and the interaction with microorganisms. Despite the importance of the contact zone, there is a lack of understanding ... -
Impact of Super Apps on the Nutrition Transition in Low- and Middle-Income Countries: Evidence from Indonesia
(2025-01-13)Many low- and middle-income countries (LMICs) are experiencing a nutrition transition from traditional diets to high-energy, processed foods, increasing non-communicable disease risks. Digitalization of food systems plays ... -
Entwicklung eines neuen Cluster-Finders für das Crystal-Barrel-Kalorimeter
(2025-01-10)Mit der experimentellen Untersuchung des Anregungsspektrums von Hadronen können Vorhersagen von Quarkmodellen sowie von Gitter-QCD-Rechnungen getestet und damit ein tieferes Verständnis der zugrundeliegenden starken ... -
Sialic acids reduction triggers complement C3-mediated microglial response and bipolar cell loss in the mouse retina
(2025-01-10)Sialic acids are sugars located at the cell surface on glycoproteins and lipids, and act as check-point inhibitors of the innate immune and complement systems. Sialic acids are abundant throughout the central nervous system, ... -
Deep-Learning-basierte Rekonstruktion zur Rauschunterdrückung und Auflösungsskalierung T2-gewichteter Sequenzen in der multiparametrischen Magnetresonanztomographie der Prostata
(2025-01-10)Die multiparametrische Magnetresonanztomographie (mpMRT) der Prostata ist die wichtigste nicht-invasive Diagnostik zur Abklärung des Prostatakarzinoms. Die Untersuchungsprotokolle sind jedoch zeitintensiv, was die Anzahl ... -
The Never-Ending Story of Authentication: Investigating Password Composition Policies and Second-Factor Recoverability
(2025-01-10)Authentication is an area where users regularly encounter IT security, and it has been studied in the field of usable IT security for at least 25 years. There are numerous proposals and ideas to improve the IT security of ... -
Impact of G-Quadruplexes on DNA damage and repair supported by the protein Zuo1 in Saccharomyces cerevisiae
(2025-01-09)The secondary structures known as G-Quadruplexes (G4s) play crucial roles in regulating biological processes such as replication, transcription, and DNA repair by folding and unfolding within specific regions of DNA. ... -
Large-scale omics-based assessments of aging trajectories in flies and mice
(2025-01-09)The significant increase in life expectancy over the past two centuries can be attributed to advancements in public health, including improved sanitation, access to clean drinking water, widespread immunization, and the ... -
The SAVED domain of the type III CRISPR protease CalpL is a ring nuclease
(2024-08-21)Prokaryotic CRISPR-Cas immune systems detect and cleave foreign nucleic acids. In type III CRISPR-Cas systems, the Cas10 subunit of the activated recognition complex synthesizes cyclic oligoadenylates (cOAs), second ...
