bonndoc - Der Publikationsserver der Universität Bonn: Recent submissions
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SciREX: Scientific Relation Extraction: Natural Language Processing Lab : final report
Karar, Sayanta; Altahan, Zyad; Aloradi, Sulaeman; Elshennawy, Abdelwahab (2025-10-24)The rapid growth of biomedical literature makes it increasingly difficult to identify and organize meaningful knowledge. This project addresses the problem by focusing on <strong>relation extraction (RE)</strong>, i.e., ... -
Pulsar timing and gravitational waves
Jang, Jiwoong (2025-10-23)Pulsars are magnetized rotating neutron stars that formed from the collapsed core of a massive star following a supernova. Charged particles are accelerated along the magnetic field lines producing electromagnetic radiation. ... -
Nahrungsmittelunverträglichkeiten bei Hashimoto-Thyreoiditis
Nazarli, Lyudmila (2025-10-23)Die Hashimoto-Thyreoiditis (HT) ist eine chronisch-entzündliche Autoimmunerkrankung der Schilddrüse, die vor allem Frauen betrifft. Auch bei euthyreoter Stoffwechsellage berichten viele Patientinnen und Patienten über ... -
Das somatische Interface: Ein Spannungsfeld von Mensch und Technologie im Zeitalter allgegenwärtiger, digitaler und opaquer Technologien
Ring, Regina (2025-10-22)Smartphones, Wearables, intelligente Umgebungen, Roboter und Künstliche Intelligenz erfassen, analysieren und interpretieren zunehmend unsere Körper. Auf diese Weise wird der Mensch selbst – mit seiner Körperlichkeit, ... -
Linking spatial patterns of the rhizosphere microbiota with photosynthate dynamics in maize roots
Schultes, Sina Rosemarie (2025-10-22)The rhizosphere serves as the boundary layer between plant roots and soil, enabling nutrient and water uptake while facilitating interactions with microorganisms through rhizodeposition. Despite its importance for plant ... -
Investigating the impact of polymorphisms in the ANKK1 and DRD2 genes on oral health-related quality of life in male patients with temporomandibular disorders
Schaffer Pugsley Baratto, Samantha; Abuabara, Allan; Cardozo Bueno, Débora Cristina; de Paris Matos, Thalita; Paiva Perin, Camila; Correr, Gisele Maria; Penazzo Lepri, César; Kirschneck, Christian; Baratto-Filho, Flares; Calvano Küchler, Erika (2025-06-20)<strong>Introduction:</strong> Previous studies have reported that genetic polymorphisms may impact the signs and symptoms of temporomandibular disorder (TMD). Therefore, this study aimed to investigate the association ... -
Blood Eosinophil Count in Asthma Is Associated With Increased Abdominal Aortic Diameter and Increased Vascular Stiffness
Biener, Leonie; Budimovska, Andrea; Skowasch, Dirk; Pizarro, Carmen; Frisch, Ben Christoph; Nickenig, Georg; Stumpf, Max Jonathan; Schaefer, Christian A.; Schahab, Nadjib (2025-02-20)<strong>Background: </strong>Asthma is associated with atherosclerosis and abdominal aortic aneurysm (AAA). However, the underlying pathomechanisms remain elusive. Blood eosinophil count (BEC) is implicated in both ... -
Beneficial effects of non-invasive physical plasma on human periodontal ligament cells in vitro
Eggers, Benedikt; Seher, Lennard; Marciniak, Jana; Pauck, Tristan; Deschner, James; Eick, Sigrun; Stope, Matthias Bernhard; Kramer, Franz-Josef; Calvano Küchler, Erika; Kirschneck, Christian; Nokhbehsaim, Marjan; Beisel-Memmert, Svenja (2024-11-19)<strong>Introduction:</strong> Periodontitis is a chronic inflammatory disease of the periodontium that can lead to the loss of affected teeth if left untreated. It is induced by a multifactorial process centered on microbial ... -
Willi Freeden, M. Zuhair Nashed: Recovery methodologies: Regularization and sampling
Witte, Bertold (2024-12-24) -
Apolipoprotein E controls Dectin-1-dependent development of monocyte-derived alveolar macrophages upon pulmonary β-glucan-induced inflammatory adaptation
Theobald, H.; Bejarano, D. A.; Katzmarski, N.; Haub, J.; Schulte-Schrepping, J.; Yu, J.; Bassler, K.; Ament, A. L.; Osei-Sarpong, C.; Piattini, F.; Vornholz, L.; T’Jonck, W.; Györfi, A. H.; Hayer, H.; Yu, X.; Sheoran, S.; Al Jawazneh, A.; Chakarov, S.; Haendler, K.; Brown, G. D.; Williams, D. L.; Bosurgi, L.; Distler, J. H. W.; Ginhoux, F.; Ruland, J.; Beyer, M. D.; Greter, M.; Bain, C. C.; Vazquez-Armendariz, A. I.; Kopf, M.; Schultze, J. L.; Schlitzer, A. (2024-04-26)The lung is constantly exposed to the outside world and optimal adaptation of immune responses is crucial for efficient pathogen clearance. However, mechanisms that lead to lung-associated macrophages' functional and ... -
First-Line Treatment for Advanced Hepatocellular Carcinoma: A Three-Armed Real-World Comparison
Mahn, Robert; Glüer, Oscar André; Sadeghlar, Farsaneh; Möhring, Christian; Zhou, Taotao; Anhalt, Thomas; Monin, Malte Benedikt; Kania, Alexander; Glowka, Tim R.; Feldmann, Georg; Brossart, Peter; Kalff, Joerg C.; Schmidt-Wolf, Ingo G. H.; Strassburg, Christian P.; Gonzalez-Carmona, Maria A. (2024-01-13)<strong>Background and Aim:</strong> There are several existing systemic 1st- line therapies for advanced hepatocellular carcinoma (HCC), including atezolizumab/bevacizumab (Atez/Bev), sorafenib and lenvatinib. This study ... -
Aberrant hippocampal Ca2+ microwaves following synapsin-dependent adeno-associated viral expression of Ca2+ indicators
Masala, Nicola; Mittag, Manuel; Ambrad Giovannetti, Eleonora; O'Neil, Darik A.; Distler, Fabian J.; Rupprecht, Peter; Helmchen, Fritjof; Yuste, Rafael; Fuhrmann, Martin; Beck, Heinz; Wenzel, Michael; Kelly, Tony (2024-07-23)Genetically encoded calcium indicators (GECIs) such as GCaMP are invaluable tools in neuroscience to monitor neuronal activity using optical imaging. The viral transduction of GECIs is commonly used to target expression ... -
Use of the FallAkte Plus System as an IT Infrastructure for the North Rhine-Westphalian General Practice Research Network: Mixed Methods Usability Study
Bozorgmehr, Arezoo; Thiem, Simon-Konstantin; Wild, Dorothea; Reinsdorff, Melanie; Vollmar, Horst Christian; Kappernagel, Annika; Schloessler, Kathrin; Weissbach, Sabine; Pentzek, Michael; Dehnen, Dorothea; Drexler, Julia; Mueller, Beate Sigrid; Pilic, Larisa; Lehmann, Lion; Loescher, Susanne; Hohmann, Elena Darinka; Frank, Friederike; Ates, Gülay; Kersten, Susanne; Mortsiefer, Achim; Aretz, Benjamin; Weltermann, Birgitta (2024-05-20)<strong>Background:</strong> Primary care research networks can generate important information in the setting where most patients are seen and treated. However, this requires a suitable IT infrastructure (ITI), which the ... -
Assessing Electronic Health Literacy in Individuals With the Post–COVID-19 Condition Using the German Revised eHealth Literacy Scale: Validation Study
Marsall, Matthias; Dinse, Hannah; Schröder, Julia; Skoda, Eva-Maria; Teufel, Martin; Bäuerle, Alexander (2024-04-25)<strong>Background:</strong> The eHealth Literacy Scale (eHEALS) is a widely used instrument for measuring eHealth literacy (eHL). However, little is known so far about whether the instrument is valid for the assessment ... -
Circular genomes of two bacterial strains capable of growing in a CO2-containing atmosphere
Heidler von Heilborn, David; Bartholomäus, Alexander; Lipski, André (2023-11-29)The bacterial strains <em>Brochothrix thermosphacta</em> DH-B18 and <em>Rathayibacter sp.</em> DH-RSZ4 were isolated from raw sausage and escalope samples and grown in a CO<sub>2</sub>-rich modified atmosphere. Here, we ... -
Prospective effects of an artificial intelligence-based computer-aided detection system for prostate imaging on routine workflow and radiologists' outcomes
Wenderott, Katharina; Krups, Jim; Luetkens, Julian A.; Gambashidze, Nikoloz; Weigl, Matthias (2023-12-06)<em>Objectives:</em> Artificial intelligence (AI) is expected to alleviate the negative consequences of rising case numbers for radiologists. Currently, systematic evaluations of the impact of AI solutions in real-world ... -
IL-6–Dependent STAT3 Activation and Induction of Proinflammatory Cytokines in Primary Sclerosing Cholangitis
Dold, Leona; Frank, Leonie; Lutz, Philipp; Kaczmarek, Dominik J.; Krämer, Benjamin; Nattermann, Jacob; Weismüller, Tobias J.; Branchi, Vittorio; Toma, Marieta; Gonzalez-Carmona, Maria; Strassburg, Christian P.; Spengler, Ulrich; Langhans, Bettina (2023-06-01)<strong>INTRODUCTION: </strong>Primary sclerosing cholangitis (PSC) is a rare cholestatic liver disease with periductal inflammation and fibrosis. Genetic studies suggest inflammatory cytokines and IL-6–dependent activation ... -
Development of the "Scale for the assessment of non-experts' AI literacy": an exploratory factor analysis
Laupichler, Matthias Carl; Aster, Alexandra; Haverkamp, Nicolas; Raupach, Tobias (2023-09-27)Artificial Intelligence competencies will become increasingly important in the near future. Therefore, it is essential that the AI literacy of individuals can be assessed in a valid and reliable way. This study presents ... -
Sustainability trade-offs in animal husbandry: Consumers' choice when they can't have it all
Klink-Lehmann, Jeanette; Tatic, Milan; Weingarten, Nina; Hartmann, Monika (2023-10-06)This paper investigates consumer choices in the presence of conflicting goals, with and without information making conflicts salient. An experimental online study was conducted with a sample of German consumers, focusing ... -
Structure-affinity and structure-residence time relationships of macrocyclic Gαq protein inhibitors
Voss, Jan H.; Crüsemann, Max; Bartling, Christian R.O.; Kehraus, Stefan; Inoue, Asuka; König, Gabriele M.; Strømgaard, Kristian; Müller, Christa E. (2023-04-21)The macrocyclic depsipeptides YM-254890 (YM) and FR900359 (FR) are potent inhibitors of Gα<sub>q/11</sub> proteins. They are important pharmacological tools and have potential as therapeutic drugs. The hydrogenated, ...





















