Auflistung nach Titel

String Compactifications from the Worldsheet and Target Space Point of View

Gerhardus, Andreas (2019-08-29)

This thesis presents research on compactifications of type II superstring theories, combining worldsheet and target space approaches. This is achieved by using supersymmetric gauge theory techniques together with geometrical ...

String dualities and superpotential

Ha, Tae-Won (2010-08-31)

The main objective of this thesis is the computation of the superpotential induced by D5-branes in the type IIB string theory and by five-branes in the heterotic string theory. Both superpotentials have the same functional ...

Strong Coupling between Small Atomic Ensembles and an Open Fiber Cavity

Gallego Fernández, Jose C. (2018-04-12)

In this work I present the experimental realization of a versatile platform for the interplay between light and matter at the single-quanta level. In particular, I demonstrate the high cooperativity of small ensembles of ...

Strongly interacting few-body systems from lattice stochastic methods

Wynen, Jan-Lukas (2020-08-04)

Lattice Monte Carlo plays an important role for non-perturbative descriptions of strong interactions. Despite its success in recent years, some fundamental challenges remain. Two of them are investigated in this work, ...

Structural Alterations of Upper Cervical Spinal Cord in Ataxic and Non-ataxic Mutation Carriers of Spinocerebellar Ataxia Type 3 (SCA3)

Koyak, Berkan Serdal Can (2022-09-22)

<strong>Objective: </strong> Spinocerebellar ataxia Type 3/Machado-Joseph disease (SCA3/MJD) is worldwide the most frequent autosomal dominantly inherited ataxia. Although the gene mutation causing SCA3 is known, there is ...

Structural and electronic decoupling of a large organic molecule from a metal surface by a single layer of hexagonal boron nitride

Brülke, Christine (2022-02-21)

In the present work, the ability of one single layer of hexagonal boron nitride (hBN) to decouple the organic molecule 3,4,9,10-perylene tetracarboxylic dianhydride (PTCDA) from an underlying Cu(111) surface was investigated. ...

Structural and Functional Changes in the Cerebellum in Sporadic Ataxias

Jiang, Xueyan (2021-01-26)

Sporadic ataxia is a group of progressive neurodegenerative diseases that can be subdivided into two groups, sporadic adult onset ataxia (SAOA), and the cerebellar type of multiple system atrophy (MSA-C). In the first years ...

Structural and functional characterization of G protein-coupled adenosine receptors and the orphan receptor GPR143

De Filippo, Elisabetta (2016-05-24)

The present thesis deals with the characterization of G protein-coupled receptors (GPCRs) and their interaction with modulators on a molecular level. We focused on the structural and functional investigation of different ...

Structural and functional characterization of human coagulation factor XIII

Singh, Sneha (2020-06-02)

The formation of a fibrin clot in blood plasma is a two-step event which involves formation of a “primary clot” comprising of fibrin polymers by from fibrin monomers under the action of thrombin and subsequently the ...

Structural and Functional Characterization of Human Transcription-regulating Kinases

Kaltheuner, Ines H. (2024-03-12)

(noch nicht zugänglich / not yet accessible)

Structural and Functional Characterization of Neurotoxic Oligomers of Pro-aggregant Tau Repeat Domain: A model for Tauopathy disease

Kaniyappan, Senthilvelrajan (2016-04-26)

Tau protein is a microtubule associated protein present abundantly in the neurons of the central nervous system where it stabilizes the axonal microtubules thereby providing structural architecture for the axons of neurons. ...

Structural and functional characterization of the HPV16 entry platform on the cell surface

Finke, Jérôme (2020-12-16)

Human papillomaviruses (HPV) are small, non-enveloped DNA viruses that infect skin and mucosa tissues. Among the family, HPV16 is one of the most oncogenic subtypes responsible for a variety of cancers, including cervical, ...

Structural and functional characterization of TRAP transporters from bacterial pathogens

Peter, Martin Friedrich (2021-08-26)

The class of tripartite ATP-independent periplasmic (TRAP) transporter proteins are wide-spread in the kingdoms of prokaryotes and archaea, where they are responsible for translo-cation of substrates across the cell membrane. ...

Structural and functional principles of long-range connectivity in the rat vibrissal system

Guest, Jason Michael (2020-11-05)

Pyramidal tract neurons (PTs) represent the major output cell type of the mammalian neocortex. Integrating feedforward thalamo-cortical (TC) and recurrent intracortical (IC) inputs with those from top down cortical-cortical ...

Structural and functional promoter analyses of epilepsy-relevant genes as basis for targeted expression interference

Tsortouktzidis, Despina (2023-07-21)

<strong>Background:</strong> Epilepsies are a group of brain disorders characterized by recurrent seizures. A fraction of those has a well defined genetic aetiology including monogenic epilepsies, and others are the result ...

Structural aspects of the plasmalemmal Amyloid Precursor Protein cluster

de Coninck, Dennis (2021-11-12)

Alzheimer’s Disease (AD) is a major socio-economic threat to health care systems and society in general. Involvement of the amyloid-beta peptide (Aβ) and its parent, the amyloid precursor protein (APP), in AD seemed obvious ...

Structural conformational analysis of molecular dynamics of a P-glycoprotein homology model and generated intermediate structures

Hafner, Melanie Salome (2019-10-02)

The major reason for failure of chemotherapy in cancer is multidrug resistance. A mechanism by which human cancers develop multi-drug resistance is over expression of certain ATP-binding cassette (ABC) transporters. ...