E-Dissertationen: Auflistung E-Dissertationen nach Titel
Anzeige der Dokumente 3635-3654 von 4118
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Systematic analysis of the synaptic recruitment and activation kinetics of presynaptic inhibitory group II metabotropic glutamate receptors
Rupprecht, Vanessa (2012-08-22)Pharmacological activation of presynaptic inhibitory group II mGluRs potently modulates excitatory synaptic transmission throughout the brain. However, little is known about the physiological conditions under which these ... -
Systematic Computational Analysis of Structure-Activity Relationships
Peltason, Lisa Bertha (2010-04-20)The exploration of structure–activity relationships (SARs) of small bioactive molecules is a central task in medicinal chemistry. Typically, SARs are analyzed on a case-by-case basis for series of closely related molecules. ... -
Systematic Identification of Scaffolds Representing Different Types of Structure-Activity Relationships
Hu, Ye (2011-07-22)In medicinal chemistry, it is of central importance to understand structure-activity relationships (SARs) of small bioactive compounds. Typically, SARs are analyzed on a case-by-case basis for sets of compounds active ... -
Systematic Study of Hadronic Molecules in the Heavy Quark Sector
Cleven, Martin (2014-01-17)In this work we have studied properties of hadronic molecules in the heavy quark sector. These have become increasingly important since from the beginning of this century a large number of states have been measured that ... -
Systematic treatment of Sematophyllaceae (Musci) in Thailand
Pollawatn, Rossarin (2008)<p>The taxonomic treatment of the Sematophyllaceae from Thailand was carried out based on about 2000 specimens. These specimens were on loan from herbaria: University of Aarhus, Denmark (AAU); Royal Forest Herbarium, Bangkok ... -
Systematics and Biogeography of the African Scaly-tailed Squirrels (Mammalia: Rodentia: Anomaluridae)
Schunke, Anja C. (2005)The aim of the present investigation was a better understanding of the systematics and biogeography of the African scaly-tailed squirrels. Therefore 1581 anomalurid specimens from 22 collections were examined and data from ... -
Systematics, Taxonomy, and Evolution of Urtica L. (Urticaceae)
Große-Veldmann, Bernadette (2017-04-25)The systematics of <i>Urtica</i> have puzzled scientists for the past 200 years and no single comprehensive attempt at understanding infrageneric relationships has been published in the past, nor have species delimitations ... -
Systematische Identifizierung und Charakterisierung ursächlich genetischer Faktoren seltener urorektaler und gastrointestinaler Fehlbildungen
Zhang, Rong (2018-07-05)Urorektale und gastrointestinale Malformationen sind menschliche Entwicklungsdefekte, die sich mit einem breiten phänotypischen Spektrum manifestieren und genetisch sehr heterogen sind. Die Ätiologie ist in den meisten ... -
Ein systematischer, linear skalierender Fragmentansatz für das Elektronenstrukturproblem
Heber, Frederik (2014-03-17)Das Elektronenstrukturproblem bezeichnet eine Familie von Gleichungen, abgeleitet von der Schrödingergleichung, welche das Verhalten von Elektronen im Potential der Atomkerne beschreiben. Zu ihr gehören die Hartree-Fock- ... -
Systemic Administration of Epothilone B Promotes Axon Regeneration and Functional Recovery after Spinal Cord Injury
Ruschel, Jörg (2014-07-07)After central nervous system (CNS) injury, such as a traumatic spinal cord injury (SCI), damaged axons fail to regenerate resulting in a permanent loss of sensorimotor functions. Regeneration is prevented by growth inhibitory ... -
T-Zellen mit komplementierenden chimären Antigen-Rezeptoren haben eine erniedrigte Aktivierungsschwelle bei der Erkennung von Antigen-Mustern
Holzinger, Astrid (2015-11-16)Die adoptive Immuntherapie mit chimären Antigen Rezeptor (CAR) modifizierten T Zellen erzielte kürzlich spektakuläre Erfolge in der Therapie leukämischer Erkrankungen, jedoch zeigten sich bei der Behandlung solider Tumore ... -
The Tagging System of the BGO-OD experiment
Messi, Francesco (2015-06-17)In the course of my PhD work, I have been involved in the development and the construction of the Tagging System for the BGO-OD experiment at the ELSA accelerators of the University of Bonn.<br /> BGO-OD is a fixed target ... -
A Tale of Two Wide Separation Gravitational Lenses
More, Anupreeta (2008)<p>Wide separation gravitational lens systems are good candidates to probe the matter (luminous+dark) distribution in massive halos. Investigation of two wide separation lens systems is carried out. MG 2016+112 is a quadruply ... -
Talentierte symbiontische Naturstoffproduzenten als Quelle neuer Wirkstoffe
Steffens, Ursula (2020-03-03)Zunehmende Resistenzen und gleichzeitig sinkende Zahlen neu zugelassener Antibiotika lassen den Bedarf an neuen antibiotischen Wirkstoffen steigen. Aber auch in anderen medizinischen Bereichen wie z. B. der Onkologie ist ... -
Taming Hadronic Effects at the Precision Frontier: From the Muon Anomaly to Rare Decays
Bai, Long (2021-02-01)The strong interaction, one of the indispensable pillars of the Standard Model of particle physics, poses challenges at low energies because of the phase transition and the confinement nature of its underlying theory, ... -
Taphonomie des Howe Quarry’s (Morrison-Formation, Oberer Jura), Bighorn County, Wyoming, USA
Michelis, Ioannis (2004)Der Howe Quarry in Nordwyoming dokumentiert ein Massenvorkommen an Sauropoden der Morrison Formation (Oberer Jura, Kimmeridgium-Tithonium). Das Ziel dieser Arbeit ist Antworten zur Paläobiologie der Sauropoden durch Studium ... -
Target-based discovery of novel inhibitors of enzymatic targets from Wolbachia endosymbionts and evaluation as antifilarial drug candidates
Lentz, Christian Stephan (2013-07-24)Filarial nematodes are the causative agents of vector-borne diseases known as lymphatic filariasis and onchocerciasis. More than 150 million inhabitants of endemic tropical and subtropical countries are infected and may ... -
Targeted Fast Radio Burst Searches with the Efflesberg 100-m Radio Telescope
Hilmarsson, Guðjón Henning (2021-03-24)Fast radio bursts (FRBs) are bright, energetic, millisecond duration radio bursts of extragalactic origin. The source of FRBs still remains an open problem. Since the discovery of FRBs in 2007, over 100 FRBs have been ... -
Targeted therapeutics against cancer and infections Identification and characterization of human ecto-nucleotidase (CD39) and coronaviral protease (Mpro) inhibitors
Schäkel, Laura Freya Andrea (2022-09-28)The main objectives of this thesis were the development, characterization and optimization of enzyme inhibitors (i) for the human ecto-nucleotidase CD39, and (ii) for the main protease of the human-pathogenic coronavirus ... -
Targeted transport of active pharmaceutical ingredients into adipose tissue
Niu, Zheming (2023-02-21)(noch nicht zugänglich / not yet accessible)