E-Dissertationen: Browsing E-Dissertationen by Title
Now showing items 1550-1569 of 4165
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Genetic modification of insulin/IGF-1 signalling promotes survival in a C. elegans model of mitochondrial dysfunction
Büttner, Sven (2016-05-17)Mitochondria are organelles in the cytoplasm of almost all eukaryotic cells. They supply large quantities of energy in the form of adenosine triphosphate (ATP) and are involved in cell signalling, differentiation and cell ... -
Genetics of schizophrenia: Contribution of rare and low-frequency sequence variants in selected genomic regions to disease susceptibility
Basmanav, Fitnat Buket (2015-03-27)Schizophrenia is a highly heritable, multifactorial mental disorder. Up to date, a number of common SNPs with low penetrance and large rare structural variants (CNVs) with higher penetrance have been identified to contribute ... -
Genome mining of marine bacteria for bioactive metabolites
Amiri Moghaddam, Jamshid (2019-02-04)Marine bacteria have come into the focus for natural product discovery as a consequence of the emergence of antibiotic resistance. This was additionally boosted by the limitations encountered in drug developments from ... -
Genome-wide screening methods in tumors of the central nervous system and cancer predisposition
Riehmer, Vera (2014-07-21)Since the development of screening methods that can be used on an exome- or genome-wide scale such as array-based comparative genomic hybridization (array-CGH) and next generation sequencing (NGS), these techniques have ... -
The Genomic Loci Cer-za and Cer-ye Contribute to Cuticular Wax Biosynthesis in Hordeum vulgare
Müller, Yannic (2022-06-28)Changing environmental conditions demand the expansion of the genetic resources to enable the rapid adaption and development of novel crop species. The cuticle as direct interface between plants and their environment is ... -
Genomweite CNV-Analyse und zielgerichtetes Next-Generation-Sequencing zur Identifizierung neuer Kandidatengene bei Patienten mit HNPCC
Kayser, Katrin (2018-01-08)In bis zu 50% der Familien mit Verdacht auf ein Lynch Syndrom (LS) kann keine zugrundeliegende Keimbahnmutation in den ursächlich bekannten Mismatch-Repair (MMR) – Genen nachgewiesen werden. Um neue ursächliche Gene für ... -
Geochemische Untersuchungen an Schwarzpeliten des Eozänen Eckfelder Maares zur Rekonstruktion der Paläoumweltbedingungen
Sabel, Martin (2006)Ca. 120 Proben aus Bohrkernen der bituminösen Laminite des Eozänen Eckfelder Maares wurden hinsichtlich ihrer Elementverteilung (C/N) sowie ihrer Kohlenstoffisotopie analysiert. An ausgewählten Proben wurden Rock-Eval-Pyrolysen ... -
Geodesics, Splines, and Embeddings in Spaces of Images
Rajković, Marko (2023-08-08)This thesis focuses on two main mathematical topics: geodesic and spline interpolation of images using the metamorphosis model, and learning low bending and low distortion image manifold embeddings. <br /> The metamorphosis ... -
Geographical perspective on antibiotic resistance in a metropolitan sewershed: Investigating socio-spatial hotspots of antibiotic use and antibiotic-resistant bacteria in Dortmund, Germany
Schmiege, Dennis (2022-02-08)Antibiotic resistance is a serious global health threat, driven by the inadequate and excessive use of antibiotics. Environmental compartments, particularly wastewater, occupy a pivotal role in the spread of antibiotic-resistant ... -
Geoinformationssysteme zur Lageanalyse und Risikobewertung
Brendel, Robert (2012-05-11)Geoinformationssysteme zur Lageanalyse und Risikobewertung sind ein wichtiges Werkzeug zur Unterstützung des Krisenmanagements. Sie liefern allen Beteiligten wichtige Hinweise und ermöglichen angemessene Reaktionen. Diese ... -
Geometric and topological recursion and invariants of the moduli space of curves
Giacchetto, Alessandro (2021-10-29)A thread common to many problems of enumeration of surfaces is the idea that complicated cases can be recovered from simpler ones through a recursive procedure. Solving the problem for the simplest topologies and expressing ... -
A geometric approach to the embedding calculus knot invariants
Kosanović, Danica (2020-10-09)In this thesis we consider two homotopy theoretic approaches to the study of spaces of knots: the theory of finite type invariants of Vassiliev and the embedding calculus of Goodwillie and Weiss, and address connections ... -
Geometric approach to the Feynman integrals
Safari, Reza (2022-10-07)In this PhD thesis, the Feynman integrals are evaluated using an algebraic geometry approach known in string theory. The GKZ description of periods and certain classes of relative periods on Calabi-Yau (<em>l</em></em> - ... -
Geometric Dilation and Halving Distance
Grüne, Ansgar (2008)Let us consider the network of streets of a city represented by a geometric graph G in the plane. The vertices of G represent the crossroads and the edges represent the streets. The latter do not have to be straight line ... -
Geometric Structures arising from Partial Differential Equations
Steinerberger, Stefan (2014-01-14)We study several geometric problems arising from partial differential equations: (1) the geometry of Laplacian Eigenfunctions on smooth, compact manifolds without boundary (2) the energy landscape of the conservation laws ... -
Geometric three-dimensional modelling of tectonic structures in the Alps and Jura Mountains
Mohammady Yosef Nejad, Seyed Davood (2021-06-01)Geometric and kinematic three-dimensional (3D) modelling of complex geological structures experienced an outstanding evolution and has become more and more important nowadays in the field of geoscience as well as oil and ... -
Geometrical Methods for the Analysis of Simulation Bundles
Iza Teran, Victor Rodrigo (2017-03-29)Efficiently analyzing large amounts of high dimensional data derived from the simulation of industrial products is a challenge that is confronted in this thesis. For this purpose, simulations are considered as abstract ... -
Geometry and derived categories of holomorphic symplectic manifolds
Beckmann, Thorsten Michael (2022-12-02)In this thesis we study various aspects of hyper-Kähler manifolds and abelian varieties such as their derived categories, sheaves, cycles, and topology. The thesis consists of six parts. <br /> The first part is mostly ... -
Geometry of random 3-manifolds
Viaggi, Gabriele (2020-01-31)We study random 3-manifolds, as introduced by Dunfield and Thurston, from a geometric point of view. Within this framework, work of Maher allows us to equip a typical random 3-manifold with a canonical geometric structure, ... -
Geometry of spaces with a synthetic lower curvature bound
Magnabosco, Mattia (2023-10-30)In recent years, several major breakthroughs in the field of geometry have been closely linked to the investigation of two pivotal topics: curvature and singularities. The objective of this thesis is to explore the geometric ...