E-Dissertationen: Auflistung E-Dissertationen nach Autor "Wachten, Dagmar"
Anzeige der Dokumente 1-7 von 7
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Action of zona pellucida glycoproteins in mouse and human sperm
Balbach, Melanie (2017-08-22)For fertilization, sperm have to penetrate the oocyte’s vestment, the zona pellucida (ZP). In mouse and human, the ZP consists of three or four different ZP glycoproteins, respectively. Binding of sperm to ZP glycoproteins ... -
Cilia-dependent signaling pathways controlling adipose tissue plasticity
Winnerling, Nora Louise (2022-11-15)Primary cilia serve as cellular antennae that detect extracellular signals and transduce this information into an intracellular response. Dysfunction of primary cilia leads to a range of severe diseases, i.e., the ... -
The Effects of Maternal Obesity on the Innate Immune System: Developmental Programming of Kupffer Cells
Balzer, Nóra Réka (2023-03-29)The global epidemic of obesity has led to an increasing number of obese women in childbearing age. It is now understood that maternal obesity has harmful consequences on fetal and adult health. The underlying mechanism of ... -
Investigating the GBA1-dependent regulation of GBA2 activity in Gaucher disease
Schonauer, Sophie (2017-08-01)Glycosphingolipids (GSLs) are a large and heterogeneous class of lipids, whose function is equally versatile and complex. They consist of a membrane anchor, ceramide, and different kinds of sugar head groups. Glucosylceramide ... -
Organization and function of signaling molecules in sperm
Hamzeh, Hussein (2017-09-15)Successful fertilization depends on the ability of sperm to locate the egg. Sperm from different species rely on diverse signaling components to gather chemical and physical cues and transduce them into a behavioral swimming ... -
The primary cilium is a unique lipid microdomain engineered to transduce extracellular cues
Kaiser, Fabian (2022-04-06)Cilia are membrane protrusions located at the surface of almost every vertebrate cell. Cilia come in two different flavors: motile cilia, which generate a fluid flow or propel cells for active movement, and immotile, also ... -
The role of GBA2 in controlling locomotor activity
Woeste, Marina Amelie (2018-12-13)Glycosphingolipids are major constituents of cellular membranes, fulfilling both structural and functional roles. Modifications of the basic glycosphingolipid glucosylceramide (GlcCer) result in numerous complex glycosylated ...