E-Dissertationen: Auflistung E-Dissertationen nach Schlagwort "G Protein-gekoppelte Rezeptoren"
Anzeige der Dokumente 1-3 von 3
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Elucidating agonist-induced signaling patterns of human G protein-coupled receptor GPR17 and uncovering pranlukast as a biased mixed agonist-antagonist at GPR17
(2011-11-15)The progress of human genome sequencing has revealed the existence of several hundred orphan G protein-coupled receptors (GPCRs), whose endogenous ligands are not yet identified, thus their deorphanization and characterization ... -
Modulation der Signaltransduktion des muskarinischen M1-Rezeptors mittels orthosterischer und dualsterischer Liganden
(2018-09-26)Muskarinische Acetylcholin Rezeptoren (mAChRs) gehören zur Superfamilie der G Protein-gekoppelten Rezeptoren (GPCRs). Der Subtyp 1 der mAChRs (M1-mAChR) koppelt bevorzugt an G Proteine der Gq-Familie, kann jedoch promiskuitiv ... -
Receptor-mediated activation and pharmacological inhibition of heterotrimeric G proteins
(2022-11-14)Heterotrimeric guanine-nucleotide binding proteins (G proteins) are key signal transducers in animal and human cells, where they forward signals transmitted by active G protein-coupled receptors (GPCRs) and trigger ...
