E-Dissertationen: Browsing E-Dissertationen by Subject "T cells"
Now showing items 1-4 of 4
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Aptamers for targeted activation of T cell-mediated immunity
Haßel, Silvana Katharina (2016-09-19)An attractive way of preventing or curing infections and diseases is to mobilize patient’s own defense mechanisms, the immune system. Treatments following this approach are commonly known as immunotherapies. The development ... -
Charakterisierung der Veto-Funktion von hepatischen Sternzellen
Schildberg, Frank Alexander (2012-08-01)Die Leber spielt eine entscheidende Rolle bei der Induktion der T-Zell-Toleranz. Diese wird insbesondere durch die Funktionen von tolerogenen hepatischen Antigen-präsentierenden Zellen und regulatorischen T-Zellen erzielt. ... -
Recognition of cytosolic 3´P DNA & The role of GCET2+ DCs in cross-presentation
Schmitt, Sven (2020-04-01)In mammalian cells, DNA is confined to the nucleus and mitochondria. Detection of DNA in other compartments like the cytoplasm indicates danger and infection. Our research group has previously discovered that 3´monophosphate ... -
Regulation of innate and adaptive immune responses by Toll-like receptor ligands
Schumak, Beatrix (2008)Toll-like receptors (TLR) recognize conserved molecular patterns of microorganisms and are essential for the activation of host immunity. Whereas the immune-stimulatory effects of TLR ligands are well described, the ...