E-Dissertationen: Search
Now showing items 21-30 of 37
Metal-Oxygen Batteries: Redox mediators and electrode characterization
(2021-02-08)
In this study some new findings on metal-oxygen batteries are presented. Tackling climate change requires a transition from the use of fossil fuels as energy sources to renewable energies. This is associated with the need ...
Die biologische Funktion der N1-2´O-Methylierung eukaryotischer mRNA durch die Methyltransferase CMTr1
(2021-05-14)
Eukaryoten modifizieren das 5´-Ende ihrer mRNA mit einem invertierten N7-methyliertem Guanosin (m7G). Diese Cap0 genannte Struktur wird in höheren Eukaryoten durch die Methyltransferase CMTr1 weiter modifiziert: CMTr1 ...
Fusogenic Liposome-Assisted Drug Delivery Across Physiological Barriers
(2021-10-18)
Fusogenic liposomes (FL) are biocompatible, cationic nano-carriers, consisting of neutral and positively charged lipids, as well as an aromatic compound. They were previously used for the delivery of nucleic acids, proteins ...
Characterization of signaling events following single-cell death in myocardial cell clusters in vitro
(2021-05-26)
Cell death is a characteristic feature of acute and chronic cardiac pathologies such as myocardial infarction, ischemia-reperfusion and heart failure. Cardiomyocytes (CMs) death triggers myocardial remodeling that may lead ...
Grundlagenuntersuchungen an modifizierten Ru und Pt Oberflächen für die Direktmethanolbrennstoffzelle
(2021-10-15)
Die vorliegende Dissertationsschrift beschreibt Grundlagenuntersuchungen an verschiedenen modifizierten Ru und Pt Oberflächen als Modellsysteme für die bimetallischen Katalysatorsysteme Se/Ru, Ru/Pt und W/Pt, die in der ...
Evolution of the Activity Cliff Concept and Practical Implications for Compound Design
(2021-07-22)
Entering the “big data” era, a number of different research areas have witnessed an enormous increase in data at an exponential rate. For drug discovery, various publicly available protein structure and compound bioactivity ...
Synthesis and reactions of Janus-type bis(NHCs), tuned by phosphorus bridges
(2021-02-15)
Due to our first attempts to synthesize P-functional bis(NHCs),[6] we were aware of a problem if bis(thiones) were used. Therefore, the idea emerged to use bis(selones) instead. Herein, the synthesis of the first tricyclic ...
Investigating 5-HT2A receptors - Development of a fluorescent 5HT2A receptor agonist and elucidation of the effects of St. John's wort extract STW3-IV, hyperforin and hyperoside on 5HT2A receptors
(2021-09-22)
Investigating 5-HT2A receptors - Development of a fluorescent 5HT2A receptor agonist and elucidation of the effects of St. John's wort extract STW3-IV, hyperforin and hyperoside on 5HT2A ...
The Influence of Solvent Reorganization on Organocatalytic Reactions
(2021-04-07)
In the last decades N-heterocyclic carbenes have shown a certain potential as organocatalysts. In addition to the formation of regio- and stereoselective C-C coupling reactions, their scope of application includes the ...
Synthese und Charakterisierung heterometallischer metallosupramolekularer Aggregate
(2021-03-09)
Diese Arbeit beschäftigt sich mit der Herstellung und der Charakterisierung heterometallischer Komplexe. Zur Konstruktion der Komplexe wurden klassische Ansätze der metallosupramolekularen Chemie, wie der Molecular-Library-Ansatz, ...