E-Dissertationen: Suche
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Evolution of DNA methylation in insects
(2021-05-21)
DNA methylation, the addition of a methyl group (-CH3) to a genomic cytosine by a DNA methyltransferase, is the most thoroughly studied epigenetic modification across eukaryotes. Functionally, it is associated with the ...
The mechanisms of stress memory responses and translational regulation during dehydration and rehydration in the resurrection plant Craterostigma plantagineum
(2020-05-25)
Dehydration stress is one of the major environmental factors affecting the survival rate and productivity of plants. Currently, many dehydration-induced genes and some dehydration-related protective mechanisms desiccation ......
Toward a precision medicine in Alzheimer’s Disease: blood phenomic fingerprint for diagnostic and therapeutic developments
(2020-05-05)
There is an unmet clinical need to identify reliable blood biomarkers for Alzheimer’s Disease (AD) that can be used for diagnostics and therapeutic purposes.
The complex nature of AD, single-readout approaches ......
The complex nature of AD, single-readout approaches ......
Influence of cyclic mechanical strain on tissues of the central nervous system
(2020-12-17)
Although the brain is the softest tissue of the human body, cells embedded in the brain are responding to physiological mechanical cues. Tissue homeostasis is, therefore, not only dependent on chemical cues (e.g. growth ...
The Acyl-ACP Thioesterase FatM from Lotus japonicus is involved in lipid transfer during Arbuscular Mycorrhiza Symbiosis
(2020-01-27)
Arbuscular mycorrhiza colonization of roots is an ancient symbiosis that presumably was involved in the conquest of the land by early plants. Its main benefit for plants is the increased access to soil mineral nutrients ...
The Phenomenon of Functional Retention of Incorporated Chloroplasts in Sea Slugs (Sacoglossa, Heterobranchia, Mollusca) and Evolutionary Adaptations: Aspects of Photobiology, Cell Biology, Ecology and Behavior
(2020-01-30)
The phenomenon of retention of functional chloroplasts from their food algae in sacoglossan sea slugs - also called kleptoplasty - is a challenge for research, still leaving many questions unsolved, e. g. concerning ......
Die biologische Funktion der N1-2´O-Methylierung eukaryotischer mRNA durch die Methyltransferase CMTr1
(2021-05-14)
Eukaryoten modifizieren das 5´-Ende ihrer mRNA mit einem invertierten N7-methyliertem Guanosin (m7G). Diese Cap0 genannte Struktur wird in höheren Eukaryoten durch die Methyltransferase CMTr1 weiter modifiziert: CMTr1 ...
Proteomic identification of posttranslational modifications: cAMP-induced changes of phosphorylation and investigation of novel approaches detecting posttranslational modifications at lysine and arginine residues
(2020-04-22)
Cyclic adenosine monophosphate (cAMP) is an important second messenger which can be generated in response to signals binding to stimulatory G-protein coupled receptors. Inside the cell, protein kinase A is a well-known ...
Impact of UGT1A polymorphisms on inflammation and fibrogenesis in a humanized transgenic mouse model
(2020-07-07)
Fibrogenesis represents a highly dynamic scarring response of the liver resulting from different causes of hepatic injury. A key process capable of activating a broad array of profibrogenic pathways is oxidative stress. ...
Entwicklung eines in vitro Testsystems zur Identifizierung pflanzlicher Signale für Mehltau (Blumeria graminis) an Weizen (Triticum aestivum)
(2021-02-11)
Blumeria graminis ist der Erreger des Echten Mehltaus an Weizen (Triticum aestivum), einer der wichtigsten Kulturpflanzen weltweit. Durch diese Pflanzenkrankheit können hohe Ernteverluste verursacht werden. Die Keimung und ......
Development of an in vitro test system to identify plant signals for powdery mildew (Blumeria graminis) on wheat (Triticum aestivum
Blumeria graminis is the causal agent of powdery mildew on wheat ......
Development of an in vitro test system to identify plant signals for powdery mildew (Blumeria graminis) on wheat (Triticum aestivum
Blumeria graminis is the causal agent of powdery mildew on wheat ......