E-Dissertationen: Search
Now showing items 21-30 of 2282
Entwicklung eines fernerkundungsgestützten Modellverbundes zur Simulation des urban-ruralen Landnutzungswandels in Nordrhein-Westfalen
(2011-07-12)
Die Veränderung der Landbedeckung und Landnutzung durch den Menschen nimmt im Zusammenhang mit der Diskussion über die Folgen des globalen Umweltwandels seit vielen Jahren eine zentrale Rolle ein. In weiten Teilen West- ...
Dynamical Studies of the Globular Cluster Systems around the Giant Elliptical Galaxies NGC4636 and NGC1399
(2011-08-02)
Dark matter studies in elliptical galaxies were long hampered by the lack of suitable dynamical tracers. The advent of 8 m-class telescopes equipped with multi-object spectrographs has made it possible to use globular ...
Contributions of keratins to epithelial cell architecture and signaling
(2011-07-04)
Keratin intermediate filament proteins form the major cytoskeleton in all epithelia. Increasing evidence suggests that keratins act as cytoskeletal scaffolds which locally regulate cell growth and survival. Many of these ...
Cytohesins are cytoplasmic ErbB receptor activators
(2011-07-12)
Signaling by ErbB receptors requires the activation of their cytoplasmic tyrosine kinase domains which is initiated by ligand binding to the receptor ectodomains. Up to now, cytoplasmic factors contributing to the activation ...
Cytosolic recognition of pathogenic nucleic acids
(2011-07-11)
The innate immune system senses pathogens by pattern recognition receptors (PRR) located in different cell compartments. Components of the bacterial cell wall and conserved proteins are detected by Toll-like receptors ...
The Semantic Shadow: Combining User Interaction with Context Information for Semantic Web-Site Annotation
(2011-07-07)
This thesis develops the concept of the Semantic Shadow (SemS), a model for managing contentual and structural annotations on web page elements and their values. The model supports a contextual weighting of the annotated ...
Validation of the novel label-free dynamic mass redistribution technology and its application for functional analysis of G protein-coupled receptors
(2011-07-04)
The dynamic mass redistribution (DMR) technology is a label-free assay platform that allows non-invasive and real-time recording of integrated cellular responses in living cells upon activation of G protein-coupled receptors ...
Influence of UV light and heat on the ferroelectric properties of lithium niobate crystals
(2011-07-04)
One of the most important non-linear-optical materials is lithium niobate, due to its ease of fabrication, robustness, transparency in the visible-to-infrared and excellent nonlinear properties. In this thesis the issue ...
Analyse von Interaktionen des Hepatoma-derived growth factors (HDGF): Identifizierung und Charakterisierung eines HDGF enthaltenden Ribonukleo-Protein-Komplexes
(2012-03-20)
Der Hepatoma-derived growth factor (HDGF) wird in vielen Tumoren verstärkt exprimiert. Die Höhe der Expression korreliert dabei in einigen Tumorarten, wie z.B. dem hepatozellulären Karzinom, mit einer schlechten Prognose ...
Untersuchungen an neuartigen Polyketidsynthasen aus marinen Schwämmen (Porifera)
(2012-03-26)
In der vorliegenden Arbeit wurden die neuartigen Polyketidsynthasen (PKS) vom SupA-Typ näher untersucht. Diese PKS wurden bisher ausschließlich in marinen Schwämmen, dort jedoch ubiquitär und häufig gefunden. Architekturell ...