E-Dissertationen: Search
Now showing items 41-50 of 71
Hydroxylation of ectoine and synthetic ectoine derivatives via E. coli-mediated whole-cell biotransformation
(2021-06-07)
The compatible solutes ectoine and hydroxyectoine are compounds mainly produced by halophilic organisms in order to prevent the loss of intracellular water when exposed to high osmotic pressure. Furthermore, these substances ......
Phenotyping of barley resistance to plant diseases on the leaf and greenhouse scale through hyperspectral imaging and data analysis
(2021-05-17)
Optical sensors become increasingly interesting as means to perform automated, non-invasive and objective monitoring in agriculture, but also have immense potential as tools for research and development. Especially ...
A role of Alzheimer’s disease-associated γ-secretase in lipid metabolism and lipid droplet formation via LXR activation
(2021-06-29)
The γ secretase is an intramembrane protease complex, essential for the processing of a wide variety of type-1 membrane proteins. Among these is the amyloid precursor protein (APP), a protein strongly linked to Alzheimer’s ...
Investigating 5-HT2A receptors - Development of a fluorescent 5HT2A receptor agonist and elucidation of the effects of St. John's wort extract STW3-IV, hyperforin and hyperoside on 5HT2A receptors
(2021-09-22)
Investigating 5-HT2A receptors - Development of a fluorescent 5HT2A receptor agonist and elucidation of the effects of St. John's wort extract STW3-IV, hyperforin and hyperoside on 5HT2A ...
Characterization of the hyperpolarization-activated, highly-selective proton channel HCNL1 found in the sperm of the zebrafish Danio rerio
(2021-04-29)
Zebrafish are external fertilizers and release their gametes into the surrounding water. Yet, the freshwater environment with its low osmolarity poses a challenge for the gametes. Given these unique ion conditions, it seems ......
Charakterisierung des hyperpolarisationsaktivierten, hochselektiven Protonenkanals HCNL1 im Spermium des Zebrafischs Danio rerio
Zebrafische pflanzen sich durch externe Befruchtung fort und geben ......
Charakterisierung des hyperpolarisationsaktivierten, hochselektiven Protonenkanals HCNL1 im Spermium des Zebrafischs Danio rerio
Zebrafische pflanzen sich durch externe Befruchtung fort und geben ......
Molecular Mechanisms of NLRP3 Inflammasome Activation: Involvement of the Leucine-Rich Repeat Domain and Charcot-Leyden Crystals
(2021-07-29)
Chronic inflammation is a major driver of several non-communicable diseases. The cytosolic pattern recognition receptor NLRP3 is involved in the development of many of these diseases, as its activation in innate immune ...
Contributions towards a better understanding of millipede phylogenetics and sawfly genomics
(2021-03-11)
A loss of biodiversity on a scale and rate comparable to the great extinction events, as a result of anthropogenic activity, has been documented for plants, animals, and micro-organisms. In order to foster a sustainable ...
Analyse der Thermostabilität mitochondrialer Proteine anhand der Protein-Disaggregation durch Hsp78 in Bäckerhefe
(2021-02-11)
Alle Organismen zeichnen sich durch spezifische auf ihre Lebensbedingungen angepasste Charakteristika aus. Hefen, darunter auch die Bäckerhefe Saccharomyces cerevisiae, besitzt eine Vielzahl an spezialisierten Proteinen, ...
Neuronal and Circuit Architecture Underlying Feeding Behavior in Drosophila
(2021-06-28)
Feeding is elemental for survival and one of the most common activities of animals. Little is known about the organization of neuronal circuits controlling feeding behavior in the cen-tral nervous system. This study maps, ...
Etablierung und Optimierung eines Produktionssystems zur Synthese des alternativen Süßstoffs 5-Ketofruktose in Gluconobacter-Stämmen
(2021-05-21)
Übergewicht, Adipositas und Diabetes sind in der heutigen Gesellschaft längst keine seltenen Krankheiten mehr. In den letzten Jahrzehnten hat die Prävalenz dieser Erkrankungen enorm zugenommen und kann mit einer zuckerreichen ......