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Mass spectrometric analysis of short-lived intermediates and ancient fossils
(2021-06-14)
The first part of this thesis focuses on mechanistic studies of two L-proline catalyzed reactions with electrospray ionization mass spectrometry. The second part describes mass spectrometric analyses of fossils, dinosaur ...
Untersuchung der molekularen Mechanismen einer Thrombozytenaktivierung durch Karzinomzellen und die Rolle des Tumormarkers MACC1 in diesem Prozess
(2023-05-31)
Die Interaktion der Tumorzellen mit Thrombozyten und die damit einhergehende Aktivierung ist ein Schlüsselfaktor der Tumormetastasierung. Die molekularen Mechanismen einer Thrombozytenaktivierung durch Tumore können sehr ...
Optimisation of the Data Reduction for the Belle II Pixel Detector and Development of a new Track Finding Algorithm using the Belle II Vertex Detector
(2023-05-15)
The Belle II experiment, located at the SuperKEKB collider in Tsukuba, Japan, is recording data at world record luminosities in order to provide world-leading results in the field of particle physics in the future. To ...
Cellular mechanoresponse to extracellular matrix shear strain and stiffness studied in a cell culture model of breast gland development
(2023-05-12)
Mechanobiological regulation is a crucial element for tissue development and homeostasis. Dysregulation of the normal mechanobiological microenvironment of cells is linked to disease and negatively affects cancer patients' ...
Machine learning approaches for adaptive optics in microscopy
(2023-05-08)
Microscopic imaging is an essential tool for science. For instruments that operate close to the physically possible diffraction limit, a main remaining challenge are aberrating operating conditions. For microscopy, such ...
Mechanistic investigations of organocatalytic and gold-catalyzed reactions and synthetic approach towards a chiral bifunctional catalyst
(2023-05-09)
The first part of this thesis focuses on the mechanistic studies of an intermolecular cyclization reaction between an α,β-unsaturated aldehyde and an electron deficient primary alkyne to a cyclopentene carbaldehyde. Based ......
Phenanthracene Nanotubes for Template-designed Organic Electronics
(2024-06-19)
The overall increasing energy consumption worldwide demands for new fundamental research that can contribute to mitigate its negative ecological effects. One such valuable field of research is the area of organic electronics. ...
Activation Mechanisms of RIG-I
(2020-11-02)
(noch nicht zugänglich / not yet accessible)
Higgs Mode and Critical Temperature in the BCS-BEC Crossover
(2024-06-19)
For this thesis, analogue quantum simulations of the BCS-BEC crossover have been performed. To this end, an ultracold gas of fermionic 6Li atoms was prepared in an optical dipole trap. The gas is in a balanced ...
Deep Representation Learning for Analyzing Financial and Cybersecurity Data
(2024-06-19)
Recent years have shown a surge in the capability of deep learning models for various domains of interest and different types of data. Machine learning models are now capable of understanding, categorizing and generating ...