E-Dissertationen: Search
Now showing items 4071-4080 of 4089
Ectopic expression of transcription factors to overcome the lineage barrier between embryonic stem cells and trophoblast stem cells in mouse and human
(2023-04-19)
The placenta is a transient organ that exhibits various essential functions during pregnancy that allow for proper development of the embryo. Placenta and embryo originate from the first lineage separation in mammalian ...
Polymer-mediated solubility enhancement and supersaturation stabilization using various hydroxypropyl cellulose grades within amorphous solid dispersions
(2024-05-14)
Solubility enhancement in combination with supersaturation stabilization of poorly soluble drugs is a well-established concept to enhance oral bioavailability. One promising formulation principle to overcome low solubility ...
The Immune Memory Response and Metabolic Requirements of Human Gamma Delta T Cells
(2024-05-14)
γδ T cells are unconventional T cells that can mediate pro-inflammatory, cytotoxic, phagocytotic and professional antigen presenting properties. Sharing the features of both adaptive and innate immunity, γδ T cells also ...
Human iPSC-derived in vitro models of the peripheral nervous system for cellular pain and somatosensation research
(2022-01-07)
The term 'somatosensation' summarizes the sensation of touch, body position, temperature and pain experienced by animals or humans. Peripheral sensory neurons can be classified according to their primary sensation as ...
Activation Mechanisms of RIG-I
(2020-11-02)
(noch nicht zugänglich / not yet accessible)
Mechanistic investigations of organocatalytic and gold-catalyzed reactions and synthetic approach towards a chiral bifunctional catalyst
(2023-05-09)
The first part of this thesis focuses on the mechanistic studies of an intermolecular cyclization reaction between an α,β-unsaturated aldehyde and an electron deficient primary alkyne to a cyclopentene carbaldehyde. Based ......
Theoretical Studies of Nuclear Magnetic Resonance Chemical Shifts
(2024-05-21)
Nuclear magnetic resonance (NMR) spectroscopy is among the most important analytical methods for the determination of the chemical structure of matter. Its versatile applicability leads to the necessity of reliable ...
Holistic Video Understanding: Spatio-Temporal Modeling and Efficiency
(2024-05-21)
Video understanding, a specialized area within computer vision, focuses on classifying human actions in video clips. The field has seen remarkable advancements, particularly with the introduction of 3D convolutional neural ...
Using real-time observations and land surface modelling for improved irrigation and water resources management in Mediterranean climate
(2024-05-21)
Irrigated agriculture is essential to sustain crop production and livelihoods of the rural population in semi-arid and arid regions such as the Mediterranean. Meanwhile, unsustainable irrigation practices, population growth, ...