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The Mannose receptor induces T cell tolerance via inhibition of CD45 and up-regulation of CTLA-4
(2014-03-28)
The present study proves that the mannose receptor (MR) bears beside its function as endocytic receptor a second responsibility namely the induction of tolerance.
The results of our experiments show that the decision, ......
The results of our experiments show that the decision, ......
Untersuchung mikrobieller Glasbildner für die Biostabilisierung und biomimetische Applikation in einem Biosensor
(2014-03-07)
Im Sinne der Bionik (biologisch inspirierte Lösungen für technische Fragestellungen) setzt sich diese Arbeit mit dem Prinzip der Vitrifikation während der Anhydrobiose auseinander. Sie ist durch die temporäre Ausbildung ......
Investigation of microbial glass-formers for biostabilisation and biomimetic application in a biosensor
In terms of bionics (biologically inspired solution for technical problems) this work investigates ......
Investigation of microbial glass-formers for biostabilisation and biomimetic application in a biosensor
In terms of bionics (biologically inspired solution for technical problems) this work investigates ......
Molekulargenetische Untersuchungen bei uro-rektalen Fehlbildungen
(2014-02-07)
Zu den schwersten angeborenen uro-rektalen Fehlbildungen zählen der Blasenekstrophie-Epispadie-Komplex (BEEK) und anorektale Malformationen (ARM). BEEK wird klinisch hinsichtlich seines Schweregrades in drei verschiedene ......
Physikochemische und biochemische Mechanismen in der Plasmamembran zur Kontrolle des Clusterverhaltens des T-Zell-Rezeptors
(2014-02-26)
Die Plasmamembran als Vermittlerin zwischen Zellinnerem und umgebender Umwelt ist eine wichtige Struktur der Zelle, deren Organisationsprinzipien nur ansatzweise verstanden sind. Membranproteine erfüllen essentielle Aufgaben ......
From cell to robot: A bio-inspired locomotion device
(2014-05-02)
Bionics or biomimetics is an interdisciplinary research field, a scientific approach to applicate naturally developed biological systems, methods and solutions to the study and design of technology and engineering systems. ...
Functional analyses of the conserved Cysteine-rich with EGF-like domains (Creld) protein family in Mus musculus
(2014-03-28)
The Cysteine-rich with EGF-like domains (Creld) protein family is highly conserved between species. However, its physiological function remained elusive. Using Creld1 knock-out (Creld1KO) mice, Creld1 was identified as an ......
The homeodomain of the Drosophila Ceramide Synthase Schlank confers nuclear import information and DNA binding capabilities
(2014-05-15)
Ceramide Synthases (CerS) are membrane bound enzymes at the center of the sphingolipid synthesis cascade. A sub-class of CerS also codes for a homeodomain of unknown function.
We previously identified the ...
We previously identified the ...
Einfluss der Johanniskrautinhaltsstoffe Hyperforin, Hyperosid und Hypericin auf die laterale Mobilität und die Signaltransduktion von 5-HT1A-Rezeptoren
(2014-05-02)
Johanniskrautextraktpräparate sind in Deutschland für die kurzzeitige Behandlung der Symptome leichter depressiver Störungen sowie für die Therapie von leichten bis mittelschweren Depressionen zugelassen. Die antidepressive ...
Ecology and Population Status of the Puku Antelope (Kobus vardonii LIVINGSTONE, 1857) in Zambia
(2014-02-18)
Road surveys along line transects were conducted at different times during the dry season. Puku occurred in small to large groups. They preferred grassland where estimated population densities were 36.15 puku/km² in Kasanka ...
Identification and molecular characterisation of unknown genes involved in desiccation tolerance mechanisms in the resurrection plant Craterostigma plantagineum
(2014-11-06)
The mechanisms that enable vegetative desiccation tolerance in the resurrection plant Craterostigma plantagineum are not fully understood. Recently, transcriptome data from this plant were obtained thus providing ...