E-Dissertationen: Search
Now showing items 1-8 of 8
Migration of interneuronal precursor cells in the developing cerebellum of mice: model-based cell tracking and simulation
(2010-12-10)
The navigation of precursor cells of inhibitory interneurons from their germinal zone inside the fourth ventricle through the white matter towards their final destination within the cerebellum's molecular layer is an ongoing ...
Computational Methods for the Integration of Biological Activity and Chemical Space
(2009-12-14)
One general aim of medicinal chemistry is the understanding of structure-activity relationships of ligands that bind to biological targets. Advances in combinatorial chemistry and biological screening technologies allow ...
Emerging Chemical Patterns for Virtual Screening and Knowledge Discovery
(2009-02-03)
The adaptation and evaluation of contemporary data mining methods to chemical and biological problems is one of major areas of research in chemoinformatics. Currently, large databases containing millions of small organic ...
AHRD: Automatically Annotate Proteins with Human Readable Descriptions and Gene Ontology Terms
(2021-10-05)
In the postgenomic era it is impossible to annotate the majority of new proteins in any other way than with computational methods. Our tool AHRD automatically annotates proteins with human readable descriptions and Gene ...
Microarrayanalyse gynäkologischer Tumorentitäten
(2013-07-10)
Softwareentwicklung Die Analyse von Genexpressionsprofilen fällt nicht länger exklusiv in den Aufgabenbereich von Bioinformatik Experten. Jedoch gestaltet sich der Erhalt von statistisch signifikanten Resultaten schwierig ......
Protein Function Prediction using Phylogenomics, Domain Architecture Analysis, Data Integration, and Lexical Scoring
(2015-03-18)
“As the number of sequenced genomes rapidly grows, the overwhelming majority of protein products can only be annotated computationally.” (Radivojac, Clark, Oron, et al. 2013) With this goal, three new protein function ...
Mathematical Analysis and Modeling of Signaling Networks
(2017-11-24)
Mathematical models are in focus of modern systems biology and increasingly important to understand and manipulate complex biological systems. At the same time, new and improved techniques in metabolomics and proteomics ...
Deep Generative Modelling in Systems Medicine: From Transcriptomics Data to Drug Development
(2024-02-02)
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