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Investigation of the endocannabinoid system using in vivo and in vitro models 

Ternes, Svenja (2013-07-31)
The endocannabinoid system (ECS) is a retrograde signaling system that plays an important, pro-homeostatic role in the central nervous system (CNS) by adjusting synaptic communication. The system comprises a set of presynaptic ...
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Loss of Inhibitory CD33 Signaling Results in Increased Microglial Activation 

Wißfeld, Jannis (2021-06-23)
CD33 is expressed on immune cells of myeloid origin, such as macrophages and microglia. Upon activation, CD33 recruits and activates protein tyrosine phosphatases, which results in attenuation of the activatory signaling ...
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Neuroinflammation in Mausmodellen der Metachromatischen Leukodystrophie 

Stein, Axel (2016-10-18)
Arylsulfatase A (ASA) katalysiert die Desulfatierung von 3-O-Sulfogalaktosylceramid (Sulfatid), einem Hauptbestandteil der Myelinscheide. Ein Verlust der Aktivität von ASA führt zu der lysosomalen Speichererkrankung ...
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The role of the endocannabinoid system in stress-related disorders and neuroimmune communication 

Beins, Eva Carolina (2020-05-04)
In the last decades, increasing evidence suggests that inflammatory processes play an important role in the development of psychiatric disorders, such as anxiety and depression. Psychosocial stress – one of the main ...
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The role of endocannabinoid system in neuron-glial communication in the ageing and diseased brain 

Ativie, Frank (2017-12-13)
The endocannabinoid system has been implicated in the regulation of glial activity and progression of brain ageing. Mice constitutively or specifically lacking the cannabinoid receptor 1 (CB1) on neurons or GABAergic neurons ...
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The role of the chemokine receptor CXCR3 in mouse models for IL-12-driven CNS-inflammation and Morbus Alzheimer-like neurodegeneration 

Krauthausen, Marius (2013-01-31)
The chemokine receptor CXCR3 and its corresponding ligands CXCL9, CXCL10 and CXCL11 are well known to be involved in the trafficking and migration of activated CD4+ Th1 T cells, CD8+ T cells and NK ......
Die Rolle des CXCR3 Rezeptors in Mausmodellen für IL-12 induzierter Neuroinflammation und Alzheimer-ähnlicher Neurodegeneration
Im Rahmen von Entzündungsreaktionen sind der Chemokinrezeptor CXCR3 und ......
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Transmission of pathogenic α-synuclein to mice 

Breid, Sara (2017-09-01)
α-Synuclein is a soluble, cellular protein that in a number of neurodegenerative diseases, including Parkinson's disease, multiple system atrophy, and Lewy body dementia aggregates into pathological protein deposits. ...
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Toward a precision medicine in Alzheimer’s Disease: blood phenomic fingerprint for diagnostic and therapeutic developments 

Al-Saeedi, Ahmed Hameed (2020-05-05)
There is an unmet clinical need to identify reliable blood biomarkers for Alzheimer’s Disease (AD) that can be used for diagnostics and therapeutic purposes.
The complex nature of AD, single-readout approaches ......
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Role of the cannabinoid receptor 2 in the development of surgical neuropathic pain 

Nent, Elisa (2018-12-12)
When normal nociceptive pain becomes chronic, it loses its protective function and causes a general pain hypersensitivity. Neuropathic pain is one type of chronic pain, which is caused by various diseases or physical injury ...
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The implication of microglial sialic acid-binding immunoglobulin-like lectin-E (Siglec-E) in neuroinflammation 

Claude, Janine (2014-03-07)
Microglia are the resident immune cells of the central nervous system (CNS). They display a whole set of recognition receptors on their cell surface to sense intact or lesioned cells in the CNS. A subfamily of these receptors ...
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Entdecke

AutorAl-Saeedi, Ahmed Hameed (1)Ativie, Frank (1)Beins, Eva Carolina (1)Breid, Sara (1)Claude, Janine (1)Krauthausen, Marius (1)Nent, Elisa (1)Stein, Axel (1)Tambe, Bertrand Agbor (1)Ternes, Svenja (1)... mehrSchlagwort
Neuroinflammation (11)
Mikroglia (4)Microglia (3)Alzheimer's disease (2)Alzheimer-Krankheit (2)Endocannabinoid system (2)microglia (2)Phagozytose (2)2-Arachidonoylglycerol (1)3D culture (1)... mehrKlassifikation (DDC)
570 Biowissenschaften, Biologie (11)
610 Medizin, Gesundheit (5)500 Naturwissenschaften (1)540 Chemie (1)... mehrPublikationstyp
Dissertation oder Habilitation (11)
... mehrErscheinungsdatum2020 - 2025 (4)2013 - 2019 (7)

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Gesamter BestandBereiche & SammlungenErscheinungsdatumAutorenTitelSchlagworteKlassifikation (DDC)PublikationstypOpen-Access-Fonds (Universität Bonn)Diese SammlungErscheinungsdatumAutorenTitelSchlagworteKlassifikation (DDC)PublikationstypOpen-Access-Fonds (Universität Bonn)

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