E-Dissertationen: Search
Now showing items 111-120 of 192
Einfluss der Johanniskrautinhaltsstoffe Hyperforin, Hyperosid und Hypericin auf die laterale Mobilität und die Signaltransduktion von 5-HT1A-Rezeptoren
(2014-05-02)
Johanniskrautextraktpräparate sind in Deutschland für die kurzzeitige Behandlung der Symptome leichter depressiver Störungen sowie für die Therapie von leichten bis mittelschweren Depressionen zugelassen. Die antidepressive ...
Ecology and Population Status of the Puku Antelope (Kobus vardonii LIVINGSTONE, 1857) in Zambia
(2014-02-18)
Road surveys along line transects were conducted at different times during the dry season. Puku occurred in small to large groups. They preferred grassland where estimated population densities were 36.15 puku/km² in Kasanka ...
Protein Function Prediction using Phylogenomics, Domain Architecture Analysis, Data Integration, and Lexical Scoring
(2015-03-18)
“As the number of sequenced genomes rapidly grows, the overwhelming majority of protein products can only be annotated computationally.” (Radivojac, Clark, Oron, et al. 2013) With this goal, three new protein function ...
Molecular mechanisms underlying presynaptic plasticity: characterization of the RIM1α and SV2A interactome
(2015-02-11)
Synaptic plasticity encompasses various cellular mechanisms, which confer synapses the ability to react and adapt to ongoing changes in network activity. Some of the suggested mechanisms include remodelling and/or assembly ...
Identification and molecular characterisation of unknown genes involved in desiccation tolerance mechanisms in the resurrection plant Craterostigma plantagineum
(2014-11-06)
The mechanisms that enable vegetative desiccation tolerance in the resurrection plant Craterostigma plantagineum are not fully understood. Recently, transcriptome data from this plant were obtained thus providing ...
The Role of TRIM71 in Male Germ Cell Development
(2020-09-02)
Germ cells are the key to continuation of life as they are the unique cell lineage capable to transfer the complete genetic information to the next generation. Both, infertility and testicular cancers are usually originating ......
Evolution der Multiresistenz bei Escherichia coli
(2005)
Ziel der Arbeit war es, am Model E. coli Spuren zu finden, wie sich im Laufe der Evolution Multiresistenz entwickelt und wie die verantwortlichen Resistenzgene im Organismus organisiert sind. Resistenten oder sogar ...
Chelation as a strategy with the potential to overcome multidrug resistance in cancer
(2016-09-02)
According to the World Health Organisation cancer is the second leading cause of death in industrialized countries. In many cases treatment fails due to the development of resistance against multiple (structurally and ...
Analysis of human T lymphocyte-derived immune responses against Staphylococcus aureus by delivery of in vitro transcribed antigens
(2016-07-06)
Staphylococcus aureus is a harmless commensal of the human mucosa and at the same time the main cause of life-threatening nosocomial infections worldwide. In particular, the growing number of methicillin-resistant S. aureus ...
Molekulare Mechanismen TNF-vermittelter viraler Hepatitis
(2016-06-10)
Zytotoxische T-Lymphozyten (CTL) eliminieren selektiv Virus-infizierte Zellen, indem sie sie anhand von viralem Antigen erkennen, das auf deren Oberfläche präsentiert wird. Eine Ausnahme bildet eine kürzlich entdeckte ...