E-Dissertationen: Suche
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The role of Trim71 in cell fate determination of embryonic stem cells and germline development
(2015-12-22)
The formation of complex tissues and organs from a limited set of stem and progenitor cells requires precise regulation of the balance between stem cell maintenance and differentiation. In the present study we introduce ......
Intensitäts- und Energieerhöhung an ELSA
(2015-12-04)
An der Elektronen-Stretcher-Anlage ELSA am Physikalischen Institut der Universität Bonn werden im Zuge des Sonderforschungsbereichs SFB/TR 16 “Elektromagnetische Anregung subnuklearer Systeme” Experimente zur Untersuchung ...
Neue Untersuchungen zur Synthese und Strukturchemie von polynären Lithium- und Silber-Übergangsmetallphosphaten
(2015-12-01)
Bei der Suche nach neuen, leistungsfähigen Kathodenmaterialien für Lithiumionenbatterien wurden im Rahmen dieser Arbeit umfangreiche Gleichgewichtsuntersuchungen in den Viertstoffsystemen Li /M / P / O (M: ...
Thermodynamically stable and metastable solids: New approaches to the synthesis of anhydrous phosphates containing vanadium, molybdenum, and/or tungsten
(2015-12-04)
This thesis reports on syntheses, crystallization, phase relations and redox phenomena in the quasi-ternary oxide systems WO2.5/VO2.5/PO2.5 and MoO2.5/VO2.5/PO2.5. ...
MicroRNAs and orphan nuclear receptor GCNF as novel regulators of human neural stem cell differentiation and neuronal subtype specification
(2015-10-22)
MicroRNAs (miRNAs) are currently recognized as important regulators of neural development. However, given the large number of miRNA species in existence, our understanding of miRNA-based regulation during neurogenesis ...
Potential of Complementary Methods for the Authentication of Herbal Substances and their Mixtures
(2015-10-22)
Herbal substances and preparations thereof play an important role in healthcare systems worldwide. An essential prerequisite for the safe and effective use of herbal medicines is the unequivocal identification of the plant ...
Oxytocin – the prosocial molecule?: Intranasal oxytocin effects on social approach behavior, social cognition, volitional and emotional ambivalence in healthy human beings
(2015-10-30)
Oxytocin (OXT) is a highly conserved neuropeptide, regarding both its chemical structure and its functionality. It has been traced back at least 700 million years. OXT’s fundamental role lies in reproduction and parenting ...
Chemical modifications of DNA activate the cGAS/STING-signaling pathway even in the presence of the cytosolic exonuclease TREX1
(2015-09-16)
To recognize pathogen threats, the innate immune system is equipped with pattern recognition receptors (PRRs) that bind to and are activated by pathogen-associated molecular patterns (PAMPs). Most PAMPs are conserved across ...
Direct and indirect cholinergic septo-hippocampal pathways cooperate to structure spiking activity in the hippocampus
(2015-10-09)
The medial septum/vertical diagonal band of Broca complex (MSvDB) is a key structure that modulates hippocampal rhythmogenesis. Cholinergic neurons of the MSvDB play a central role in generating and pacing theta-band ...
Immune modulation by experimental filarial infection and its impact on E. coli-induced sepsis
(2015-11-12)
Helminths cause so-called neglected tropical diseases in tropical and sub-tropical regions and are prevalent in almost one third of mankind. Thus, co-infections of helminths with other pathogens are common. However, the ......