E-Dissertationen: Search
Now showing items 11-15 of 15
Proteomic identification of posttranslational modifications: cAMP-induced changes of phosphorylation and investigation of novel approaches detecting posttranslational modifications at lysine and arginine residues
(2020-04-22)
Cyclic adenosine monophosphate (cAMP) is an important second messenger which can be generated in response to signals binding to stimulatory G-protein coupled receptors. Inside the cell, protein kinase A is a well-known ...
Mechanistic Investigation of a HAuCl4 catalyzed oxidative C-C coupling reaction and Synthesis of new supramolecular Silver(I) and Gold(I) NHC compounds: or handling of a Mass Spectrometric Challenge and catching Counterions on Supramolecular Playgrounds
(2021-04-22)
Reaction monitoring by electrospray (ESI) mass spectrometry is a valuable technique to investigate reaction mechanisms. It allows a glimpse into the reacting solution and the characterization of transient intermediates ......
Quantum Chemical Calculation of Electron Ionization Mass Spectra
(2018-03-06)
This thesis reports the computation of electron ionization (EI) mass spectra using a method that combines statistical theory and molecular dynamics. Due to the complexity of the unimolecular reaction space, not all competing ......
Computation of Mass Spectra Using Quantum Chemical Methods
(2022-11-23)
Mass spectrometry (MS) is widely used for the structural elucidation of compounds in a vast variety of scientific research. Unfortunately, many methods that aim to predict mass spectra cannot often elucidate the complete ...
Mechanistic investigations of organocatalytic and gold-catalyzed reactions and synthetic approach towards a chiral bifunctional catalyst
(2023-05-09)
The first part of this thesis focuses on the mechanistic studies of an intermolecular cyclization reaction between an α,β-unsaturated aldehyde and an electron deficient primary alkyne to a cyclopentene carbaldehyde. Based ......